We performed a genome-wide transmission disequilibrium test analysis of a newly genotyped autism case-parent triad samples (127 trios) in Han Chinese, identified top association signals at multiple single nucleotide polymorphisms (SNPs), including rs9839376 (OR = 2.59, P = 1.27 × 10<sup>-05</sup> ) at KCNMB2, rs6044680 (OR = 0.319, P = 4.82 × 10<sup>-05</sup> ) and rs7274133 (OR = 0.313, P = 3.22 × 10<sup>-05</sup> ) at PCSK2, and rs310619 (OR = 2.40, P = 7.44 × 10<sup>-05</sup> ) at EEF1A2.