Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs763361
rs763361
0.090 GeneticVariation BEFREE Moreover, co-engagement of the TCR and a risk variant of CD226 that is associated with autoimmunity (rs763361) further enhanced VAV1 activation and IL-17 production. 29991650

2018

dbSNP: rs763361
rs763361
0.090 GeneticVariation BEFREE This meta-analysis provided evidence that CD226 Gly307Ser (rs763361) is significantly associated with the risk of multiple autoimmune diseases. 23073294

2013

dbSNP: rs763361
rs763361
0.090 GeneticVariation BEFREE This meta-analysis demonstrates the CD226 rs763361 polymorphism confers susceptibility to autoimmune disease in Europeans, South Americans and Asians, and in particular, shows that the CD226 rs763361 polymorphism is associated with SLE, SSc and T1D. 22941566

2012

dbSNP: rs763361
rs763361
0.090 GeneticVariation BEFREE A novel non-synonymous (Gly307Ser) variant, rs763361, of the CD226 gene on chromosome 18q22 was recently shown to be associated with multiple autoimmune diseases. 20887380

2011

dbSNP: rs763361
rs763361
0.090 GeneticVariation BEFREE The nonsynonymous polymorphism rs763361 of the CD226 gene, which encodes DNAX accessory molecule 1, which is involved in T cell costimulation pathways, has recently been identified as a genetic risk factor for autoimmunity. 21162102

2011

dbSNP: rs763361
rs763361
0.090 GeneticVariation BEFREE A nonsynonymous polymorphism in exon 7 of the gene encoding the lymphocyte cell-surface CD226 (DNAM1) receptor, Gly307Ser (rs763361), has recently been identified as conferring risk to many autoimmune disorders. 21521299

2011

dbSNP: rs763361
rs763361
0.090 GeneticVariation BEFREE Our results demonstrate that the coding variant rs763361 in CD226 gene is associated with multiple ADs in non-European populations. 20338887

2010

dbSNP: rs763361
rs763361
0.090 GeneticVariation BEFREE CD226 Gly307Ser association with multiple autoimmune diseases. 18971939

2009

dbSNP: rs763361
rs763361
0.090 GeneticVariation BEFREE Recently, there has been increasing evidence that a non-synonymous exchange (Gly307Ser) in the gene for CD226 is linked to several autoimmune diseases including type 1 diabetes, multiple sclerosis (MS), rheumatoid arthritis and Grave's disease. 19536154

2009