|
rs1203334353
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two variants, c.671A>G (p.(Asn224Ser)) in DMRT1 and c.91C>T (p.(Arg31Cys)) in REC8, have already been described in association with azoospermia.
|
31479588 |
2020 |
|
rs140506267
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two variants, c.671A>G (p.(Asn224Ser)) in DMRT1 and c.91C>T (p.(Arg31Cys)) in REC8, have already been described in association with azoospermia.
|
31479588 |
2020 |
|
rs140506267
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two variants, c.671A>G (p.(Asn224Ser)) in DMRT1 and c.91C>T (p.(Arg31Cys)) in REC8, have already been described in association with azoospermia.
|
31479588 |
2020 |
|
rs34075659
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two variants, c.671A>G (p.(Asn224Ser)) in DMRT1 and c.91C>T (p.(Arg31Cys)) in REC8, have already been described in association with azoospermia.
|
31479588 |
2020 |
|
rs150771661
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our early studies revealed a missense mutation (R242H) of GRTH in 5.8% of Japanese patient population with azoospermia.
|
31040297 |
2019 |
|
rs26279
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The genotype frequency distribution of rs26279 (A>G) in MSH3 was found to be significantly different between IMI and control (p < 0.05), as well as azoospermia.
|
31342644 |
2019 |
|
rs6166
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We evaluated the association of the single-nucleotide polymorphisms (SNP) FSHB -211G>T (rs10835638), FSHR -29G>A (rs1394205), and FSHR c.2039A>G (rs6166) with testicular histopathology and SRR in patients with azoospermia.
|
30668782 |
2019 |
|
rs10129954
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Also, a statistically significant association between rs10129954 and azoospermia, and oligozoospermia was observed.
|
28975488 |
2018 |
|
rs11531577
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No significant differences in allele and genotype frequencies of SNP rs1050482 and rs11531577 in STAG3 gene as well as rs2288846 in RFX2 gene between patients with azoospermia and controls were observed.
|
29277047 |
2018 |
|
rs12348
|
|
|
0.010 |
GeneticVariation |
BEFREE |
When we assessed the relationship between rs12348 in TUSC1 and rs2772579 in IZUMO3 and male infertility traits, we found that rs12348 in TUSC1 was significantly associated with azoospermia and oligozoospermia, but rs2772579 in IZUMO3 was not associated with male infertility.
|
28975488 |
2018 |
|
rs2070744
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The aim of this study was to assess the possible association of three genetic variants (rs2070744, rs1799983 and intron variant 4a/4b) in NOS3 gene and infertility occurrence in two groups of infertile men (idiopathic azoospermia and oligoasthenozoospermia) and fertile controls.
|
28466478 |
2018 |
|
rs2288846
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No significant differences in allele and genotype frequencies of SNP rs1050482 and rs11531577 in STAG3 gene as well as rs2288846 in RFX2 gene between patients with azoospermia and controls were observed.
|
29277047 |
2018 |
|
rs4045481
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The polymorphism of SNP rs4045481 in RNF212 gene might be associated with azoospermia and genotype CC of this SNP may be a risk factor of azoospermia.
|
29277047 |
2018 |
|
rs68073206
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We addressed the functional consequences of SNP rs68073206, located at the +5 position of an alternative 5' splice donor site, and observed its association with male infertility in the subjects with azoospermia, oligoasthenozoospermia and normozoospermia.
|
28367994 |
2017 |
|
rs11614913
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In following stratified analysis, we found that rs11614913 exhibited a significantly higher risk of asthenospermia, oligozoospermia and azoospermia.
|
26805933 |
2016 |
|
rs222859
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association of G/T(rs222859) polymorphism in Exon 1 of YBX2 gene with azoospermia, among Iranian infertile males.
|
26804374 |
2016 |
|
rs11204546
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Clinically, the SNPs (rs11204546 of OR2W3 and rs11677854 of GTF2A1L ) might be additional valuable molecular predictive markers for assessing the treatment of NOA patients.
|
25374392 |
2015 |
|
rs11677854
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Clinically, the SNPs (rs11204546 of OR2W3 and rs11677854 of GTF2A1L ) might be additional valuable molecular predictive markers for assessing the treatment of NOA patients.
|
25374392 |
2015 |
|
rs1335054067
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This novel mutation (p. V385L) of DAX-1 is the first to be identified in association with secretory azoospermia, thereby highlighting the important role of DAX-1 in spermatogenesis.
|
26207377 |
2015 |
|
rs1801394
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The polymorphic distributions of the four SNPs (MTHFR C677T and A1298C, MTR A2756G and MTRR A66G) were investigated by the method of SNaPshot in a Chinese cohort including 296 idiopathic infertile males with azoospermia or oligozoospermia and 204 fertile males.
|
25578539 |
2015 |
|
rs1805087
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The polymorphic distributions of the four SNPs (MTHFR C677T and A1298C, MTR A2756G and MTRR A66G) were investigated by the method of SNaPshot in a Chinese cohort including 296 idiopathic infertile males with azoospermia or oligozoospermia and 204 fertile males.
|
25578539 |
2015 |
|
rs55763075
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results indicated that the MTHFR 3'-UTR rs55763075 polymorphism might modify the susceptibility to male infertility with idiopathic azoospermia.
|
26505368 |
2015 |
|
rs724078
|
|
|
0.010 |
GeneticVariation |
BEFREE |
There were no associations between rs724078 and azoospermia or oligozoospermia.
|
25908656 |
2015 |
|
rs769642496
|
|
|
0.010 |
GeneticVariation |
BEFREE |
1) A novel variant in exon 1 (p.Pro130Leu) that disrupted a mammalian specific polyproline stretch in the self-association domain was more frequent in azoospermia cases (0.27% vs 0.13%, p = 0.549).
|
25451826 |
2015 |
|
rs7867029
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The SNPs rs7867029 and rs7174015 are associated with oligozoospermia [rs7867029: odds ratio (OR) = 1.70, 95% confidence interval (CI) = 1.07-2.68, P = 0.024 (log-additive); rs7174015: OR = 6.52, 95% CI = 1.57-27.10, P = 0.0099 (dominant)] and rs12870438 is associated with azoospermia (OR = 10.90, 95% CI = 2.67-44.60, P = 0.00087 (recessive)] and oligozoospermia [OR = 8.54, 95% CI = 1.52-47.90, P = 0.015 (recessive)].
|
25908656 |
2015 |