rs769642496
|
|
|
0.010 |
GeneticVariation |
BEFREE |
1) A novel variant in exon 1 (p.Pro130Leu) that disrupted a mammalian specific polyproline stretch in the self-association domain was more frequent in azoospermia cases (0.27% vs 0.13%, p = 0.549).
|
25451826 |
2015 |
rs201438485
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A 46,XY female with complete gonadal dysgenesis carried a p.K320R mutation in the highly conserved NAP domain, and a 46,XY male with idiopathic azoospermia harbored a p.R89H mutation, and this data supports the hypothesis that mutations in TSPYL1 may contribute to anomalies of testicular development/function.
|
19463995 |
2009 |
rs10842262
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
A genome-wide association study in Chinese men identifies three risk loci for non-obstructive azoospermia.
|
22197933 |
2011 |
rs12097821
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
A genome-wide association study in Chinese men identifies three risk loci for non-obstructive azoospermia.
|
22197933 |
2011 |
rs2477686
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
A genome-wide association study in Chinese men identifies three risk loci for non-obstructive azoospermia.
|
22197933 |
2011 |
rs6080550
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
A genome-wide association study in Chinese men identifies three risk loci for non-obstructive azoospermia.
|
22197933 |
2011 |
rs10129954
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Also, a statistically significant association between rs10129954 and azoospermia, and oligozoospermia was observed.
|
28975488 |
2018 |
rs222859
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association of G/T(rs222859) polymorphism in Exon 1 of YBX2 gene with azoospermia, among Iranian infertile males.
|
26804374 |
2016 |
rs11204546
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Clinically, the SNPs (rs11204546 of OR2W3 and rs11677854 of GTF2A1L ) might be additional valuable molecular predictive markers for assessing the treatment of NOA patients.
|
25374392 |
2015 |
rs11677854
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Clinically, the SNPs (rs11204546 of OR2W3 and rs11677854 of GTF2A1L ) might be additional valuable molecular predictive markers for assessing the treatment of NOA patients.
|
25374392 |
2015 |
rs2207396
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Compared with those with the GG genotype, patients being heterozygous for the A allele in rs2207396 had a significantly increased risk of azoospermia [odds ratio (OR): 3.8; 95% confidence interval: 1.5-9.5; P=0.008], this OR being even higher in the subgroup treated with alkylating drugs (OR: 8.8; 95% confidence interval: 2.1-36; P=0.004).
|
21430602 |
2011 |
rs1800477
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Considering the decreased antiapoptotic function of BCL2, these results suggest that the Ala43Thr variant is associated with protection against azoospermia in the Han-Chinese population.
|
20610805 |
2010 |
rs25487
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In a selected Chinese population, AA genotype of Arg399Gln appears to contribute to a decreased risk of idiopathic azoospermia, while we have not any evidence of involvement of XRCC1 T-77C and Arg194Trp polymorphisms in idiopathic azoospermia.
|
17968463 |
2007 |
rs1799782
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In a selected Chinese population, AA genotype of Arg399Gln appears to contribute to a decreased risk of idiopathic azoospermia, while we have not any evidence of involvement of XRCC1 T-77C and Arg194Trp polymorphisms in idiopathic azoospermia.
|
17968463 |
2007 |
rs25487
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In conclusion, the SNP locus rs25487 of XRCC1 could be a marker for genetic susceptibility to idiopathic azoospermia and the A allele might be a risk gene of idiopathic azoospermia in the northern Chinese Han population.
|
22868082 |
2012 |
rs1217691063
|
|
|
0.050 |
GeneticVariation |
BEFREE |
In conclusion, this meta-analysis is in favor that the MTHFR C677T polymorphism is capable of causing male infertility susceptibility, especially in Asians and the subgroup of azoospermia.
|
26584688 |
2016 |
rs397507444
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In conclusion, this meta-analysis supports that the MTHFR A1298C polymorphism is capable of causing male infertility susceptibility, especially azoospermia.
|
22175540 |
2012 |
rs9340958
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In ERα, markers of one specific haplotype block (rs2207396, rs9340958, rs9340978) were associated with an increased risk of azoospermia.
|
21430602 |
2011 |
rs9340978
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In ERα, markers of one specific haplotype block (rs2207396, rs9340958, rs9340978) were associated with an increased risk of azoospermia.
|
21430602 |
2011 |
rs11614913
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In following stratified analysis, we found that rs11614913 exhibited a significantly higher risk of asthenospermia, oligozoospermia and azoospermia.
|
26805933 |
2016 |
rs1799983
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In this study, the polymorphic distributions of three common polymorphism loci including T-786C, 4A4B and G894T in eNOS gene were investigated in 355 Chinese infertile patients with azoospermia or oligozoospermia and 246 healthy fertile men and a meta-analysis was carried in order to explore the possible relationship between the three loci of eNOS gene and male infertility with spermatogenesis impairment.
|
23756085 |
2013 |
rs1217691063
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Influence of methylenetetrahydrofolate reductase C677T gene polymorphisms in Algerian infertile men with azoospermia or severe oligozoospermia.
|
22928696 |
2012 |
rs1217691063
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Meta-analysis revealed an association by use of fixed-effects model of MTHFR C677T with the risk of azoospermia.
|
24268703 |
2014 |
rs777919630
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Meta-analysis revealed an association by use of fixed-effects model of MTHFR C677T with the risk of azoospermia.
|
24268703 |
2014 |
rs11531577
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No significant differences in allele and genotype frequencies of SNP rs1050482 and rs11531577 in STAG3 gene as well as rs2288846 in RFX2 gene between patients with azoospermia and controls were observed.
|
29277047 |
2018 |