|
rs12097821
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
A genome-wide association study in Chinese men identifies three risk loci for non-obstructive azoospermia.
|
22197933 |
2011 |
|
rs724078
|
|
|
0.010 |
GeneticVariation |
BEFREE |
There were no associations between rs724078 and azoospermia or oligozoospermia.
|
25908656 |
2015 |
|
rs1800477
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Considering the decreased antiapoptotic function of BCL2, these results suggest that the Ala43Thr variant is associated with protection against azoospermia in the Han-Chinese population.
|
20610805 |
2010 |
|
rs144848
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The results of this study suggested that the polymorphism N372H in BRCA2 gene may be associated with idiopathic male infertility with azoospermia or severe oligozoospermia.
|
16257105 |
2006 |
|
rs777919630
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Meta-analysis revealed an association by use of fixed-effects model of MTHFR C677T with the risk of azoospermia.
|
24268703 |
2014 |
|
rs121918346
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results show that the T54A polymorphism in DAZL has no major role in Japanese males with azoospermia or oligozoospermia.
|
16123080 |
2005 |
|
rs150771661
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our early studies revealed a missense mutation (R242H) of GRTH in 5.8% of Japanese patient population with azoospermia.
|
31040297 |
2019 |
|
rs140506267
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two variants, c.671A>G (p.(Asn224Ser)) in DMRT1 and c.91C>T (p.(Arg31Cys)) in REC8, have already been described in association with azoospermia.
|
31479588 |
2020 |
|
rs140506267
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two variants, c.671A>G (p.(Asn224Ser)) in DMRT1 and c.91C>T (p.(Arg31Cys)) in REC8, have already been described in association with azoospermia.
|
31479588 |
2020 |
|
rs2228611
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To explore the relationship between DNMT1 and spermatogenesis impairment, polymorphic distributions of single-nucleotide polymorphisms (SNP) rs16999593, rs2228612 and rs2228611 in DNMT1 were investigated in 342 infertile patients with idiopathic azoospermia or oligospermia and 232 fertile controls in a Chinese population.
|
24631383 |
2014 |
|
rs1203334353
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two variants, c.671A>G (p.(Asn224Ser)) in DMRT1 and c.91C>T (p.(Arg31Cys)) in REC8, have already been described in association with azoospermia.
|
31479588 |
2020 |
|
rs2070565
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These results indicated that SNP rs2070565, as well as haplotypes AAA and GAA, may be associated with male infertility and suggest that DNMT3L may contribute to azoospermia susceptibility in humans.
|
22116073 |
2012 |
|
rs10129954
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Also, a statistically significant association between rs10129954 and azoospermia, and oligozoospermia was observed.
|
28975488 |
2018 |
|
rs12870438
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The association between rs7174015 and oligozoospermia under a dominant model and between rs12870438 and azoospermia under additive and recessive models remained after correction for multiple testing.
|
25908656 |
2015 |
|
rs12870438
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Of these, three SNPs (rs7867029, rs7174015, and rs12870438) were found to be significantly associated with the risk of azoospermia and/or oligozoospermia in a Japanese population.
|
28975488 |
2018 |
|
rs1799793
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study was designed to examine whether ERCC1 polymorphisms 3 UTR (C8092A), Asn118Asn (G19007A) and ERCC2 polymorphisms Asp312Asn (G-->A), Lys751Gln (A-->C), which have been reported to contribute to some cancers, are associated with idiopathic azoospermia in the Chinese population.
|
18616887 |
2008 |
|
rs13181
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study was designed to examine whether ERCC1 polymorphisms 3 UTR (C8092A), Asn118Asn (G19007A) and ERCC2 polymorphisms Asp312Asn (G-->A), Lys751Gln (A-->C), which have been reported to contribute to some cancers, are associated with idiopathic azoospermia in the Chinese population.
|
18616887 |
2008 |
|
rs2207396
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Compared with those with the GG genotype, patients being heterozygous for the A allele in rs2207396 had a significantly increased risk of azoospermia [odds ratio (OR): 3.8; 95% confidence interval: 1.5-9.5; P=0.008], this OR being even higher in the subgroup treated with alkylating drugs (OR: 8.8; 95% confidence interval: 2.1-36; P=0.004).
|
21430602 |
2011 |
|
rs9340958
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In ERα, markers of one specific haplotype block (rs2207396, rs9340958, rs9340978) were associated with an increased risk of azoospermia.
|
21430602 |
2011 |
|
rs9340978
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In ERα, markers of one specific haplotype block (rs2207396, rs9340958, rs9340978) were associated with an increased risk of azoospermia.
|
21430602 |
2011 |
|
rs6166
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We evaluated the association of the single-nucleotide polymorphisms (SNP) FSHB -211G>T (rs10835638), FSHR -29G>A (rs1394205), and FSHR c.2039A>G (rs6166) with testicular histopathology and SRR in patients with azoospermia.
|
30668782 |
2019 |
|
rs11677854
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Clinically, the SNPs (rs11204546 of OR2W3 and rs11677854 of GTF2A1L ) might be additional valuable molecular predictive markers for assessing the treatment of NOA patients.
|
25374392 |
2015 |
|
rs553509
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These results indicated that the polymorphism -9C>T and 368A>G in H2BFWT gene are associated with male infertility with idiopathic azoospermia or oligozoospermia, suggesting that H2BFWT gene might be contribute to susceptibility to spermatogenesis impairment in Chinese population.
|
22509975 |
2012 |
|
rs11614913
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In following stratified analysis, we found that rs11614913 exhibited a significantly higher risk of asthenospermia, oligozoospermia and azoospermia.
|
26805933 |
2016 |
|
rs4474514
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To explore the possible association of KIT and KITLG genes with male infertility having spermatogenesis impairment, polymorphism distributions of SNP rs3819392 in KIT gene as well as rs995030 and rs4474514 in KITLG gene were investigated in 372 patients with idiopathic azoospermia or oligospermia and 205 fertile controls.
|
24083421 |
2013 |