|
rs10842262
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
A genome-wide association study in Chinese men identifies three risk loci for non-obstructive azoospermia.
|
22197933 |
2011 |
|
rs12097821
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
A genome-wide association study in Chinese men identifies three risk loci for non-obstructive azoospermia.
|
22197933 |
2011 |
|
rs2477686
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
A genome-wide association study in Chinese men identifies three risk loci for non-obstructive azoospermia.
|
22197933 |
2011 |
|
rs6080550
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
A genome-wide association study in Chinese men identifies three risk loci for non-obstructive azoospermia.
|
22197933 |
2011 |
|
rs1217691063
|
|
|
0.050 |
GeneticVariation |
BEFREE |
In conclusion, this meta-analysis is in favor that the MTHFR C677T polymorphism is capable of causing male infertility susceptibility, especially in Asians and the subgroup of azoospermia.
|
26584688 |
2016 |
|
rs1217691063
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Our meta-analysis showed that the MTHFR C677T mutation was a risk factor for male infertility in both azoospermia and oligoasthenoteratozoospermia patients, especially in Asian population.
|
26549413 |
2015 |
|
rs1217691063
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Meta-analysis revealed an association by use of fixed-effects model of MTHFR C677T with the risk of azoospermia.
|
24268703 |
2014 |
|
rs1217691063
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Influence of methylenetetrahydrofolate reductase C677T gene polymorphisms in Algerian infertile men with azoospermia or severe oligozoospermia.
|
22928696 |
2012 |
|
rs1217691063
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Single nucleotide polymorphism C677T in the methylenetetrahydrofolate reductase gene might be a genetic risk factor for infertility for Chinese men with azoospermia or severe oligozoospermia.
|
16888682 |
2007 |
|
rs12870438
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Of these, three SNPs (rs7867029, rs7174015, and rs12870438) were found to be significantly associated with the risk of azoospermia and/or oligozoospermia in a Japanese population.
|
28975488 |
2018 |
|
rs1799983
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The aim of this study was to assess the possible association of three genetic variants (rs2070744, rs1799983 and intron variant 4a/4b) in NOS3 gene and infertility occurrence in two groups of infertile men (idiopathic azoospermia and oligoasthenozoospermia) and fertile controls.
|
28466478 |
2018 |
|
rs7174015
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Of these, three SNPs (rs7867029, rs7174015, and rs12870438) were found to be significantly associated with the risk of azoospermia and/or oligozoospermia in a Japanese population.
|
28975488 |
2018 |
|
rs12870438
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The association between rs7174015 and oligozoospermia under a dominant model and between rs12870438 and azoospermia under additive and recessive models remained after correction for multiple testing.
|
25908656 |
2015 |
|
rs7174015
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The association between rs7174015 and oligozoospermia under a dominant model and between rs12870438 and azoospermia under additive and recessive models remained after correction for multiple testing.
|
25908656 |
2015 |
|
rs1799983
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In this study, the polymorphic distributions of three common polymorphism loci including T-786C, 4A4B and G894T in eNOS gene were investigated in 355 Chinese infertile patients with azoospermia or oligozoospermia and 246 healthy fertile men and a meta-analysis was carried in order to explore the possible relationship between the three loci of eNOS gene and male infertility with spermatogenesis impairment.
|
23756085 |
2013 |
|
rs397507444
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Pooled estimate on c.1298A>C data from all published studies including our data showed no association of this polymorphism with male infertility (Odds ratio = 1.035, P = 0.56), azoospermia (Odds ratio = 0.97, P = 0.74), or oligoasthenoteratozoospermia (Odds ratio = 0.92, p = 0.29).
|
23874907 |
2013 |
|
rs2075789
|
|
|
0.020 |
GeneticVariation |
BEFREE |
One intronic SNP in MLH1 (rs4647269) and two non-synonymous SNPs in PMS2 (rs1059060, Ser775Asn) and MSH5 (rs2075789, Pro29Ser) seem to be risk factors for the development of azoospermia or oligozoospermia.
|
22594646 |
2012 |
|
rs25487
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In conclusion, the SNP locus rs25487 of XRCC1 could be a marker for genetic susceptibility to idiopathic azoospermia and the A allele might be a risk gene of idiopathic azoospermia in the northern Chinese Han population.
|
22868082 |
2012 |
|
rs397507444
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In conclusion, this meta-analysis supports that the MTHFR A1298C polymorphism is capable of causing male infertility susceptibility, especially azoospermia.
|
22175540 |
2012 |
|
rs2075789
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The role of MSH5 C85T and MLH3 C2531T polymorphisms in the risk of male infertility with azoospermia or severe oligozoospermia.
|
19808033 |
2010 |
|
rs25487
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In a selected Chinese population, AA genotype of Arg399Gln appears to contribute to a decreased risk of idiopathic azoospermia, while we have not any evidence of involvement of XRCC1 T-77C and Arg194Trp polymorphisms in idiopathic azoospermia.
|
17968463 |
2007 |
|
rs1203334353
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two variants, c.671A>G (p.(Asn224Ser)) in DMRT1 and c.91C>T (p.(Arg31Cys)) in REC8, have already been described in association with azoospermia.
|
31479588 |
2020 |
|
rs140506267
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two variants, c.671A>G (p.(Asn224Ser)) in DMRT1 and c.91C>T (p.(Arg31Cys)) in REC8, have already been described in association with azoospermia.
|
31479588 |
2020 |
|
rs140506267
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two variants, c.671A>G (p.(Asn224Ser)) in DMRT1 and c.91C>T (p.(Arg31Cys)) in REC8, have already been described in association with azoospermia.
|
31479588 |
2020 |
|
rs34075659
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two variants, c.671A>G (p.(Asn224Ser)) in DMRT1 and c.91C>T (p.(Arg31Cys)) in REC8, have already been described in association with azoospermia.
|
31479588 |
2020 |