|
rs4986790
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Toll-like receptor 4 D299G polymorphism could influence not only the predisposition to bacterial infections but also the evolution of the disease in cirrhotic patients.
|
20222908 |
2010 |
|
rs4986790
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Two single nucleotide polymorphisms (SNPs) encoding Asp299Gly and Thr399Ile substitutions in the TLR4 ectodomain were previously associated with TLR4 hyporesponsiveness and increased susceptibility to bacterial infection.
|
17709532 |
2007 |
|
rs4986790
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Polymorphisms in TLR2 (Arg753Gln) and TLR4 (Asp299Gly, Thr399Ile) genes are associated with bacterial infections, we therefore studied these polymorphisms in osteomyelitis patients.
|
16487238 |
2006 |
|
rs2476601
|
|
|
0.020 |
GeneticVariation |
BEFREE |
A single-nucleotide polymorphism (SNP) C1858T located on this gene has been associated with autoimmune diseases and bacterial infections.
|
19115939 |
2008 |
|
rs2476601
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The PTPN22 R620W polymorphism is associated with severe bacterial infections after human leukocyte antigen geno-identical haematopoietic stem-cell transplantations.
|
18580482 |
2008 |
|
rs4986791
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Two single nucleotide polymorphisms (SNPs) encoding Asp299Gly and Thr399Ile substitutions in the TLR4 ectodomain were previously associated with TLR4 hyporesponsiveness and increased susceptibility to bacterial infection.
|
17709532 |
2007 |
|
rs5743708
|
|
|
0.020 |
GeneticVariation |
BEFREE |
These results have indicated that there is a strong significant relationship between susceptibility to recurrent bacterial infections and Arg753Gln polymorphism of the TLR-2 gene.
|
17554618 |
2007 |
|
rs4986791
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Polymorphisms in TLR2 (Arg753Gln) and TLR4 (Asp299Gly, Thr399Ile) genes are associated with bacterial infections, we therefore studied these polymorphisms in osteomyelitis patients.
|
16487238 |
2006 |
|
rs5743708
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Polymorphisms in TLR2 (Arg753Gln) and TLR4 (Asp299Gly, Thr399Ile) genes are associated with bacterial infections, we therefore studied these polymorphisms in osteomyelitis patients.
|
16487238 |
2006 |
|
rs1061170
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A case-control method (488 septic patients and 527 healthy individuals) was carried out in this study to investigate the genetic relationship between CFH polymorphisms (rs3753394 C/T, rs1065489 G/T and rs1061170 C/T) and susceptibility to sepsis caused by bacterial infections in Chinese Han populations.
|
31525397 |
2020 |
|
rs1065489
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A case-control method (488 septic patients and 527 healthy individuals) was carried out in this study to investigate the genetic relationship between CFH polymorphisms (rs3753394 C/T, rs1065489 G/T and rs1061170 C/T) and susceptibility to sepsis caused by bacterial infections in Chinese Han populations.
|
31525397 |
2020 |
|
rs3827440
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The results suggest that ITM2A might be a susceptibility gene for GD in the Xq21.1 locus, and environmental factors, such as viral and bacterial infections, probably contribute to GD pathogenesis by interacting with the risk SNP rs3827440 mediating the regulation of ITM2A expression.
|
27809695 |
2017 |
|
rs6876739
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Using expression quantitative trait loci (eQTL) analysis, we found that the C7 rs6876739 CC genotypes and mannan-binding lectin (MBL2) gene polymorphisms of liver donors were significantly associated with bacterial infection in recipients.
|
27063552 |
2016 |
|
rs1426866722
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Inactive forms of Rac, including the human Rac2(D57N) mutant, disrupted the TRAF6-ECSIT complex by sequestering TRAF6 and substantially diminished ROS production and enhanced susceptibility to bacterial infection.
|
26414765 |
2015 |
|
rs373495105
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Inactive forms of Rac, including the human Rac2(D57N) mutant, disrupted the TRAF6-ECSIT complex by sequestering TRAF6 and substantially diminished ROS production and enhanced susceptibility to bacterial infection.
|
26414765 |
2015 |
|
rs4794067
|
|
|
0.010 |
GeneticVariation |
BEFREE |
TBX21-1993T/C (rs4794067) polymorphism is associated with increased risk of chronic periodontitis and increased T-bet expression in periodontal lesions, but does not significantly impact the IFN-g transcriptional level or the pattern of periodontophatic bacterial infection.
|
25832120 |
2015 |
|
rs74315507
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Inactive forms of Rac, including the human Rac2(D57N) mutant, disrupted the TRAF6-ECSIT complex by sequestering TRAF6 and substantially diminished ROS production and enhanced susceptibility to bacterial infection.
|
26414765 |
2015 |
|
rs3796508
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These results provide new insight into the pathophysiologic role of TLR6 V327M in the innate immune response to bacterial infection in human.
|
24797996 |
2014 |
|
rs2066844
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The mutated NOD2 R702W genotype in the recipient is independently associated with an increased risk of bacterial infections after liver transplantation, indicating a predisposing role for this genetic factor impairing the recipient's innate immune system.
|
23977330 |
2013 |
|
rs1475539937
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Recently we have shown an association of a TLR3 receptor variant, L412F, to susceptibility to chronic candidiasis, recurrent viral and bacterial infections and autoimmunity.
|
22024499 |
2012 |
|
rs3775291
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Recently we have shown an association of a TLR3 receptor variant, L412F, to susceptibility to chronic candidiasis, recurrent viral and bacterial infections and autoimmunity.
|
22024499 |
2012 |
|
rs762513613
|
|
|
0.010 |
GeneticVariation |
BEFREE |
FcgammaRIIa (CD32) contains a polymorphic variant (H/R131) that has been associated with variability in susceptibility to both bacterial diseases and Plasmodium falciparum parasitemia.
|
14740869 |
2003 |