rs924080
|
|
|
0.840 |
GeneticVariation |
BEFREE |
Of these 5 loci, 2 were found to be significantly associated with BD susceptibility: rs17375018 (G vs. A, OR = 1.50, 95% CI: 1.34-1.68, <i>P</i> < .00001) and rs924080 (T vs. C, OR = 1.36, 95% CI: 1.29-1.43, <i>P</i> < .00001).
|
31814470 |
2019 |
rs924080
|
|
|
0.840 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease.
|
20622878 |
2010 |
rs924080
|
|
|
0.840 |
GeneticVariation |
BEFREE |
SNPs (rs924080 and rs11209032) of the IL23R-IL12RB2 region were found to be associated with BD in a Northern Chinese Han population.
|
27660093 |
2016 |
rs924080
|
|
|
0.840 |
GeneticVariation |
BEFREE |
Our findings not only confirmed the association of IL10/rs1800871 and IL23R-IL12RB2/rs924080 with BD but also identified 2 susceptibility single nucleotide polymorphisms in IL10 and IL23R-IL12RB2 (rs3024490 and rs12141431) with BD in Han Chinese.
|
27464962 |
2017 |
rs924080
|
|
|
0.840 |
GeneticVariation |
BEFREE |
Six SNPs in IL23R-IL12RB2 were found to be associated with BD after Bonferroni correction for multiple testing, the most significant of which were rs17375018 (OR for G allele 1.51, 95% CI 1.27-1.78, P(unadj) = 1.93 × 10(-6) ), rs7517847 (OR for T allele 1.48, 95% CI 1.26-1.74, P(unadj) = 1.23 × 10(-6) ), and rs924080 (OR for T allele 1.29, 95% CI 1.20-1.39, P = 1.78 × 10(-5) ).
|
22378604 |
2012 |
rs924080
|
|
|
0.840 |
GeneticVariation |
GWASCAT |
Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease.
|
20622878 |
2010 |
rs1495965
|
|
|
0.820 |
GeneticVariation |
BEFREE |
SNPs rs10489629, rs1343151, and rs1495965 were also significantly associated with BD in all tests performed.
|
22378604 |
2012 |
rs1495965
|
|
|
0.820 |
GeneticVariation |
BEFREE |
An IL23R-IL12RB2 intergenic SNP rs1495965 was significantly associated with BD risk (OR (95% CI) = 1.5 (1.3, 1.7), P = 2.5 × 10<sup>-7</sup>) in the pooled meta-analysis of the discovery (1.4 (1.2, 1.7), P = 4.9 × 10<sup>-7</sup>) and replication (1.9 (1.3, 2.6), P = 6.0 × 10<sup>-4</sup>) phases.
|
29017598 |
2017 |
rs1495965
|
|
G |
0.820 |
GeneticVariation |
GWASCAT |
Genome-wide association studies identify IL23R-IL12RB2 and IL10 as Behçet's disease susceptibility loci.
|
20622879 |
2010 |
rs1495965
|
|
G |
0.820 |
GeneticVariation |
GWASDB |
Genome-wide association studies identify IL23R-IL12RB2 and IL10 as Behçet's disease susceptibility loci.
|
20622879 |
2010 |
rs4947296
|
|
|
0.800 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies GIMAP as a novel susceptibility locus for Behcet's disease.
|
23041938 |
2013 |
rs4947296
|
|
|
0.800 |
GeneticVariation |
GWASDB |
Identification of a susceptibility locus in STAT4 for Behçet's disease in Han Chinese in a genome-wide association study.
|
23001997 |
2012 |
rs4947296
|
|
|
0.800 |
GeneticVariation |
GWASCAT |
Identification of a susceptibility locus in STAT4 for Behçet's disease in Han Chinese in a genome-wide association study.
|
23001997 |
2012 |
rs9266406
|
|
|
0.800 |
GeneticVariation |
GWASCAT |
Identification of a susceptibility locus in STAT4 for Behçet's disease in Han Chinese in a genome-wide association study.
|
23001997 |
2012 |
rs9266406
|
|
|
0.800 |
GeneticVariation |
GWASDB |
Identification of a susceptibility locus in STAT4 for Behçet's disease in Han Chinese in a genome-wide association study.
|
23001997 |
2012 |
rs9266406
|
|
|
0.800 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies GIMAP as a novel susceptibility locus for Behcet's disease.
|
23041938 |
2013 |
rs10236188
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies GIMAP as a novel susceptibility locus for Behcet's disease.
|
23041938 |
2013 |
rs10256482
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies GIMAP as a novel susceptibility locus for Behcet's disease.
|
23041938 |
2013 |
rs10277380
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies GIMAP as a novel susceptibility locus for Behcet's disease.
|
23041938 |
2013 |
rs1522596
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies GIMAP as a novel susceptibility locus for Behcet's disease.
|
23041938 |
2013 |
rs1916012
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies GIMAP as a novel susceptibility locus for Behcet's disease.
|
23041938 |
2013 |
rs2253907
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies GIMAP as a novel susceptibility locus for Behcet's disease.
|
23041938 |
2013 |
rs2253907
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Identification of a susceptibility locus in STAT4 for Behçet's disease in Han Chinese in a genome-wide association study.
|
23001997 |
2012 |
rs2517411
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies GIMAP as a novel susceptibility locus for Behcet's disease.
|
23041938 |
2013 |
rs2848479
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Genetic Analysis with the Immunochip Platform in Behçet Disease. Identification of Residues Associated in the HLA Class I Region and New Susceptibility Loci.
|
27548383 |
2016 |