Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs924080
rs924080
0.840 GeneticVariation BEFREE Of these 5 loci, 2 were found to be significantly associated with BD susceptibility: rs17375018 (G vs. A, OR = 1.50, 95% CI: 1.34-1.68, <i>P</i> < .00001) and rs924080 (T vs. C, OR = 1.36, 95% CI: 1.29-1.43, <i>P</i> < .00001). 31814470

2019

dbSNP: rs924080
rs924080
0.840 GeneticVariation BEFREE Our findings not only confirmed the association of IL10/rs1800871 and IL23R-IL12RB2/rs924080 with BD but also identified 2 susceptibility single nucleotide polymorphisms in IL10 and IL23R-IL12RB2 (rs3024490 and rs12141431) with BD in Han Chinese. 27464962

2017

dbSNP: rs924080
rs924080
0.840 GeneticVariation BEFREE SNPs (rs924080 and rs11209032) of the IL23R-IL12RB2 region were found to be associated with BD in a Northern Chinese Han population. 27660093

2016

dbSNP: rs924080
rs924080
0.840 GeneticVariation BEFREE Six SNPs in IL23R-IL12RB2 were found to be associated with BD after Bonferroni correction for multiple testing, the most significant of which were rs17375018 (OR for G allele 1.51, 95% CI 1.27-1.78, P(unadj) = 1.93 × 10(-6) ), rs7517847 (OR for T allele 1.48, 95% CI 1.26-1.74, P(unadj) = 1.23 × 10(-6) ), and rs924080 (OR for T allele 1.29, 95% CI 1.20-1.39, P = 1.78 × 10(-5) ). 22378604

2012

dbSNP: rs924080
rs924080
0.840 GeneticVariation GWASCAT Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease. 20622878

2010

dbSNP: rs924080
rs924080
0.840 GeneticVariation GWASDB Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease. 20622878

2010

dbSNP: rs1800871
rs1800871
0.830 GeneticVariation BEFREE Our findings not only confirmed the association of IL10/rs1800871 and IL23R-IL12RB2/rs924080 with BD but also identified 2 susceptibility single nucleotide polymorphisms in IL10 and IL23R-IL12RB2 (rs3024490 and rs12141431) with BD in Han Chinese. 27464962

2017

dbSNP: rs1518111
rs1518111
0.830 GeneticVariation BEFREE Interestingly, we have found, majority of the tribal populations have low frequency of VL ('A' of rs3024498); and high frequency of leprosy ('T' of rs1554286), and Behcet's ('A' of rs1518111) associated alleles, whereas these were vice versa in castes. 25941808

2015

dbSNP: rs1800871
rs1800871
0.830 GeneticVariation BEFREE Compared to the controls, an increased frequency of the rs1800871 T allele was observed in BD patients with extraocular findings, including genital ulcers, skin lesions, and a positive pathergy test. 26015771

2015

dbSNP: rs1518111
rs1518111
0.830 GeneticVariation BEFREE Similarly, rs1518111, which showed strong linkage disequilibrium (r(2)=1) with allele rs1800871, was also associated with BD (pc=0.026). 24269690

2014

dbSNP: rs1800871
rs1800871
0.830 GeneticVariation BEFREE Similarly, rs1518111, which showed strong linkage disequilibrium (r(2)=1) with allele rs1800871, was also associated with BD (pc=0.026). 24269690

2014

dbSNP: rs1800871
rs1800871
0.830 GeneticVariation GWASDB Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B*51 and ERAP1. 23291587

2013

dbSNP: rs1518111
rs1518111
0.830 GeneticVariation BEFREE In IL10, rs1518111 was nominally associated with BD before and after adjustment for population stratification (odds ratio [OR] for T allele 1.20, 95% confidence interval [95% CI] 1.02-1.40, unadjusted P [P(unadj) ] = 2.53 × 10(-2) ; adjusted P [P(adj) ] = 1.43 × 10(-2) ), and rs1554286 demonstrated a trend toward association (P(unadj) = 6.14 × 10(-2) ; P(adj) = 3.21 × 10(-2) ). 22378604

2012

dbSNP: rs1518111
rs1518111
0.830 GeneticVariation GWASCAT Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease. 20622878

2010

dbSNP: rs1518111
rs1518111
0.830 GeneticVariation GWASDB Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease. 20622878

2010

dbSNP: rs1800871
rs1800871
T 0.830 GeneticVariation GWASCAT Genome-wide association studies identify IL23R-IL12RB2 and IL10 as Behçet's disease susceptibility loci. 20622879

2010

dbSNP: rs1800871
rs1800871
T 0.830 GeneticVariation GWASDB Genome-wide association studies identify IL23R-IL12RB2 and IL10 as Behçet's disease susceptibility loci. 20622879

2010

dbSNP: rs17482078
rs17482078
0.820 GeneticVariation BEFREE Although preliminary, our data show a stronger association of rs17482078 with BS compared to rs27044 by means of case-control genetic analysis and bioinformatics prediction of protein structure change. 30820838

2019

dbSNP: rs1495965
rs1495965
0.820 GeneticVariation BEFREE An IL23R-IL12RB2 intergenic SNP rs1495965 was significantly associated with BD risk (OR (95% CI) = 1.5 (1.3, 1.7), P = 2.5 × 10<sup>-7</sup>) in the pooled meta-analysis of the discovery (1.4 (1.2, 1.7), P = 4.9 × 10<sup>-7</sup>) and replication (1.9 (1.3, 2.6), P = 6.0 × 10<sup>-4</sup>) phases. 29017598

2017

dbSNP: rs2617170
rs2617170
0.820 GeneticVariation BEFREE Significantly increased frequencies of the A allele as well as AA genotype of rs1800450 in MBL2 (Pc = 2.50 × 10<sup>-6</sup>, OR = 1.494; Pc = 2.24 × 10<sup>-6</sup>,OR = 2.899; respectively) and TT genotype of rs2617170 in KLRC4 (Pc = 2.53 × 10<sup>-6</sup>, OR = 1.695) and decreased frequencies of GG genotype of rs1800450 (Pc = 1.56 × 10-3, OR = 0.689) and C allele as well as CC genotype of rs2617170 (Pc = 2.05 × 10-9,OR = 0.664; Pc = 1.20 × 10-5, OR = 0.585; respectively) were observed in BD. 28706259

2017

dbSNP: rs2617170
rs2617170
0.820 GeneticVariation BEFREE For all 6 SNPs tested by meta-analysis (Pmeta ), the association with BD was strengthened, because the direction and magnitude of association were similar across populations (e.g., for rs7574070, odds ratio [OR] for A allele 1.29 [95% confidence interval (95% CI) 1.21-1.37], Pmeta  = 2.34 × 10(-16) ; for rs7616215, OR for C allele 0.70 [95% CI 0.65-0.76], Pmeta  = 1.54 × 10(-19) ; for rs17810546, OR for A allele 0.60 [95% CI 0.52-0.70], Pmeta  = 6.34 × 10(-11) ; for rs2617170, OR for T allele 0.76 [95% CI 0.70-0.81], Pmeta  = 2.75 × 10(-14) ; for rs13154629, OR for TT genotype 2.76 [95% CI 2.01-3.80], Pmeta  = 3.57 × 10(-10) ). 26097239

2015

dbSNP: rs17482078
rs17482078
0.820 GeneticVariation BEFREE Our aim was, the replication in the Spanish population of the association described in the Turkish population between ERAP1 (rs17482078) and BD. 25019531

2014

dbSNP: rs17482078
rs17482078
T 0.820 GeneticVariation GWASDB Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B*51 and ERAP1. 23291587

2013

dbSNP: rs17482078
rs17482078
T 0.820 GeneticVariation GWASCAT Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B*51 and ERAP1. 23291587

2013

dbSNP: rs2617170
rs2617170
T 0.820 GeneticVariation GWASCAT Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B*51 and ERAP1. 23291587

2013