Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs10509906
rs10509906
0.020 GeneticVariation BEFREE Though we failed to replicate the individual association of rs10509906 to disease, the intragenic epistatic effect between rs10509906 and rs2501577 was suggested as exhibiting susceptibility to BA, further cross-validated by multifactor dimensionality reduction (MDR) (<i>P</i>=0.068, OR = 1.37), which may explain extra hidden heritability of <i>ADD3</i> to BA. 29685956

2018

dbSNP: rs2501577
rs2501577
0.020 GeneticVariation BEFREE Two SNPs in <i>ADD3</i> were replicated as associated with BA (1.60E-04 ≤ <i>P</i>≤1.70E-04, 1.33 ≤ odds ratio (OR) ≤ 1.58 for rs17095355, 2.10E-04 ≤ <i>P</i>≤5.30E-04, 1.26 ≤ OR ≤ 1.57 for rs2501577</span>). 29685956

2018

dbSNP: rs2501577
rs2501577
0.020 GeneticVariation BEFREE SNP-SNP interaction analysis showed that the SNP combination of the two genes rs17095355 and rs2501577 provided an additive increase in BA risk. 29508064

2018

dbSNP: rs10509906
rs10509906
0.020 GeneticVariation BEFREE This study suggests that the ADD3 gene plays an important role in BA pathogenesis and reveals a significant association between two SNPs, rs17095355 and rs10509906, and BA. 25285724

2014