|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Val66Met polymorphism of the BDNF gene may be associated with cognitive performance on the WCST in bipolar mood disorder but not in schizophrenia.
|
16472361 |
2006 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
DNA samples from the Treatment of Early Age Mania (TEAM) and Mayo Clinic Bipolar Disorder Biobank were investigated for association of rs6265 with early-onset bipolar disorder.
|
26528762 |
2015 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Effects of the brain-derived neurotrophic growth factor val66met variation on hippocampus morphology in bipolar disorder.
|
18704093 |
2009 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Association between brain-derived neurotrophic factor genetic polymorphism Val66Met and susceptibility to bipolar disorder: a meta-analysis.
|
25539739 |
2014 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Our study also adds to the body of evidence associating the functional Val66Met polymorphism of BDNF with BD.
|
22085476 |
2012 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
BDNF rs6265 was associated with St in the BD group (p = 0.017).
|
30041166 |
2017 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
BDNF Val66Met polymorphism and bipolar disorder in European populations: A risk association in case-control, family-based and GWAS studies.
|
27236043 |
2016 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Few genetic studies exploring the impact of Val66Met on cognition in BD.
|
30078664 |
2019 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Further studies are needed to evaluate the genetic association between the val66met allele and the BD-PTSD population, along with central/peripheral BDNF levels and epigenetic patterns of BDNF gene regulation within these patients.
|
21931317 |
2012 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Lithium response and Val66Met polymorphism of the brain-derived neurotrophic factor gene in Japanese patients with bipolar disorder.
|
16538178 |
2006 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Haplotype analysis of marker combination rs988748-(GT)n-rs6265 produced nominally significant associations for all investigated phenotypes (global p values: MDD p = .00006, BPAD p = .0057, schizophrenia p = .016).
|
16005437 |
2005 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We performed a family-based association study and ETDT analyses of the Val66Met polymorphism in 312 BD nuclear families, and compared allele-specific mRNA levels in both post-mortem brain samples and B lymphoblasts from BD patients and controls.
|
18606495 |
2008 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Val66Met polymorphism and serum brain-derived neurotrophic factor in bipolar disorder: an open-label trial.
|
23957567 |
2014 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Here we investigated a two hit gene environment model in relation to functional genomic factors (BDNF mRNA), and volume of hippocampal subfields in schizophrenia spectrum and bipolar disorders, focusing on both an environmental (childhood trauma) and genetic risk factor (BDNF val66met).
|
25246365 |
2014 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The val66met single-nucleotide polymorphism (SNP) showed significant (P = 0.005) association for valine (allele G) with schizophrenia but not bipolar disorder.
|
15630410 |
2005 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The aim of the present study was to examine the interplay between the BDNF Val(66)Met polymorphism and stressful life events (SLEs) in bipolar disorder.
|
20172611 |
2010 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Meta-analysis reveals no association of the Val66Met polymorphism of brain-derived neurotrophic factor with either schizophrenia or bipolar disorder.
|
17417060 |
2007 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Our study suggests that the markers examined thus far in COMT and SLC6A4 are not associated with pediatric bipolar disorder and that if the val66met marker in BDNF is associated with pediatric bipolar disorder the magnitude of the association is much smaller than first reported.
|
19193231 |
2009 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Changes in gyrification over 4 years in bipolar disorder and their association with the brain-derived neurotrophic factor valine(66) methionine variant.
|
19167700 |
2009 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The BDNF Val66Met polymorphism and plasma brain-derived neurotrophic factor levels in Han Chinese patients with bipolar disorder and schizophrenia.
|
24468644 |
2014 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We investigated the neurochemistry of the left dorsolateral prefrontal cortex of bipolar disorder and healthy participants in relation to the brain-derived neurotrophic factor val66met polymorphism using H-magnetic resonance spectroscopy.
|
17885603 |
2007 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Although the present study has some limitations, the results indicate a lack of association between the Val66Met polymorphism and bipolar disorder</span>.
|
25041243 |
2015 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The BDNF val66met polymorphism is a potential vulnerability factor for cognitive impairment in BD.
|
24862657 |
2014 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We examined the association between the BDNF Val66Met and DRD3 Ser9Gly polymorphisms with two subtypes of bipolar disorder: bipolar-I and -II.
|
22877924 |
2012 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Variation at the Val66Met polymorphism of BDNF does not play a major role in influencing susceptibility to bipolar disorder as a whole, but is associated with susceptibility to the rapid-cycling subset of the disorder.
|
16388065 |
2006 |