rs759834365
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0.100 |
GeneticVariation |
BEFREE |
Although the present study has some limitations, the results indicate a lack of association between the Val66Met polymorphism and bipolar disorder</span>.
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25041243 |
2015 |
rs759834365
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0.100 |
GeneticVariation |
BEFREE |
Here we investigated a two hit gene environment model in relation to functional genomic factors (BDNF mRNA), and volume of hippocampal subfields in schizophrenia spectrum and bipolar disorders, focusing on both an environmental (childhood trauma) and genetic risk factor (BDNF val66met).
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25246365 |
2014 |
rs759834365
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0.100 |
GeneticVariation |
BEFREE |
We aimed to explore whether anxiety in BD offspring was associated with the BDNF Val66Met polymorphism.64 BD offspring (mean age: 13.73 (S.D.
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25498133 |
2015 |
rs759834365
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0.100 |
GeneticVariation |
BEFREE |
Association between brain-derived neurotrophic factor genetic polymorphism Val66Met and susceptibility to bipolar disorder: a meta-analysis.
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25539739 |
2014 |
rs759834365
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0.100 |
GeneticVariation |
BEFREE |
Association of brain-derived neurotrophic factor (BDNF) Val66Met polymorphism with early-onset bipolar disorder.
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26528762 |
2015 |
rs759834365
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0.100 |
GeneticVariation |
BEFREE |
Previous studies investigated the impact of brain-derived neurotrophic factor (BDNF) val66met (rs6265) on hippocampus volumes and neurocognition in bipolar disorders (BD), but the results were not consistent.
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27018938 |
2016 |
rs759834365
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0.100 |
GeneticVariation |
BEFREE |
Although the Val66Met polymorphism at the BDNF gene does not seem to play a significant role in children and adolescents with BD or ADHD, BDNF serum levels deserve further attention in future research on neurobiological aspects of BD and ADHD.
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27209073 |
2016 |
rs759834365
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0.100 |
GeneticVariation |
BEFREE |
BDNF Val66Met polymorphism and bipolar disorder in European populations: A risk association in case-control, family-based and GWAS studies.
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27236043 |
2016 |
rs759834365
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0.100 |
GeneticVariation |
BEFREE |
We concluded that changes in plasma BDNF levels significantly correlated with changes in WCST scores in BD and is moderated by the BDNF Val66Met polymorphism and the subtype of BD.
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27905499 |
2016 |
rs759834365
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0.100 |
GeneticVariation |
BEFREE |
Twenty-six gene variants were investigated across candidate gene studies and 4 studies used a genome-wide association approach.Replicated evidence (i.e. in >2 studies) suggests that individuals with BD carrying the BDNF Val66Met risk allele could have reduced hippocampal volumes compared to non-carriers.
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28479278 |
2017 |
rs759834365
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0.100 |
GeneticVariation |
BEFREE |
Few genetic studies exploring the impact of Val66Met on cognition in BD.
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30078664 |
2019 |