Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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0.080 | GeneticVariation | BEFREE | It indicated that XRCC1 R399Q and R194W might not be risk factors to bladder cancer, but the 399QQ genotype decreased susceptibility of bladder cancer under recessive model and homozygote contrast among ever-smokers. | 18765423 | 2008 |
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0.080 | GeneticVariation | BEFREE | For Arg(194)Trp (six studies, 3091 cases, 3219 controls), no evidence indicated that individuals carrying the variant genotypes (Trp/Trp + Arg/Trp), relative to those carrying the wild homozygote Arg/Arg genotype, had a decreased risk of bladder cancer (odds ratio [OR] 0.90, 95% confidence interval [CI] 0.77 to 1.05; P = 0.17). | 18336890 | 2008 |
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0.080 | GeneticVariation | BEFREE | However, the XRCC1 R194W and R280H polymorphisms were both associated with increased bladder cancer risk among Asians. | 24039945 | 2013 |
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0.080 | GeneticVariation | BEFREE | The meta-analysis results suggest that XRCC1 Arg194Trp and Arg399Gln polymorphisms may be associated with elevated bladder cancer risk. | 23496911 | 2013 |
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0.080 | GeneticVariation | BEFREE | Our meta-analysis shows that XRCC1 Arg194Trp and Arg280His polymorphisms are associated with a significantly increased risk of bladder cancer in Asian population. | 23704969 | 2013 |
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0.080 | GeneticVariation | BEFREE | Our meta-analysis results suggest that XRCC1 Arg194Trp and Arg280His polymorphisms are associated with significantly increased risk of bladder cancer in Asians. | 23636799 | 2013 |
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0.080 | GeneticVariation | BEFREE | This meta-analysis suggested that XRCC1 Arg194Trp and Arg280His polymorphisms were risk factors for increasing bladder cancer in Asian population. | 24266849 | 2013 |
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0.080 | GeneticVariation | BEFREE | APEX1 rs3136817, MUTYH rs3219493, three SNPs (rs3213356, rs25487 and rs1799782) in XRCC1, and three SNPs (rs1799794, rs861531 and rs861530) in XRCC3 showed significant associations with the risk of bladder cancer. | 27153553 | 2016 |