| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | GeneticVariation | BEFREE | P53 Arg72Pro or codon 72 polymorphism has been indicated to increase the risk of developing certain cancers such as bladder cancer and cervical cancer. | 26123760 | 2015 |
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0.080 | GeneticVariation | BEFREE | We have reported previously that the TP53 codon72 polymorphism (rs1042522) is associated with the incidence and invasiveness of bladder cancer in a Han Chinese population. | 22178231 | 2013 |
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|
0.080 | GeneticVariation | BEFREE | Subgroup analyses by ethnicity showed that TP53 Arg72Pro polymorphism contributed to bladder cancer</span> risk in East Asians in three genetic models (For Pro vs. Arg, Fixed-effects OR 1.18, 95 % CI 1.05-1.32; For ProPro vs. ArgArg, Fixed-effects OR 1.40, 95 % CI 1.11-1.77; For ProPro vs. ArgPro/ArgArg, Fixed-effects OR 1.32, 95 % CI 1.07-1.62). | 23184052 | 2013 |
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|
0.080 | GeneticVariation | BEFREE | This meta-analysis suggests that p53 Arg72Pro polymorphism is associated with increased risk of bladder cancer in Asians. | 23073555 | 2013 |
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|
0.080 | GeneticVariation | BEFREE | P53 Arg72Pro polymorphism and bladder cancer risk--meta-analysis evidence for a link in Asians but not Caucasians. | 22901221 | 2012 |
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|
0.080 | GeneticVariation | BEFREE | The role of TP53 PRO47SER and ARG72PRO single nucleotide polymorphisms in the susceptibility to bladder cancer. | 19523860 | 2011 |
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0.080 | GeneticVariation | BEFREE | Thus, it is evident from our study that Arg72Pro SNP is implicated in bladder cancer, and that the rare, proline-related allele is connected with higher susceptibility to bladder cancer. | 21156242 | 2010 |
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|
0.080 | GeneticVariation | BEFREE | Meta-analysis of association between TP53 Arg72Pro polymorphism and bladder cancer risk. | 20630574 | 2010 |