Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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0.070 | GeneticVariation | BEFREE | Among four DNA repair gene polymorphisms, the OGG1 326 Ser/Cys and XPD 312 Asp/Asn heterozygous genotypes might be recognized as potential genetic markers modifying susceptibility to bladder cancer in Belarus. | 25089939 | 2014 |
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0.070 | GeneticVariation | BEFREE | In conclusion, our results suggest that hOGG1 Ser326Cys polymorphism may contribute to the susceptibility to bladder cancer in a Chinese population. | 22463382 | 2012 |
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0.070 | GeneticVariation | BEFREE | Overall, no significant association between the hOGG1 Ser326Cys polymorphism and bladder cancer</span> risk was found for Cys/Cys vs Ser/Ser (OR = 1.10, 95%CI = 0.74-1.65), Ser/Cys vs Ser/Ser (OR = 1.07, 95%CI = 0.81-1.42), Cys/Cys + Ser/Cys vs Ser/Ser (OR = 1.08, 95%CI = 0.87-1.33), and Cys/Cys vs Ser/Cys + Ser/Ser (OR = 1.04, 95%CI = 0.65-1.69). | 23079842 | 2012 |
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0.070 | GeneticVariation | BEFREE | This meta-analysis suggests that the hOGG1 Ser326Cys polymorphism may be a risk factor for bladder cancer without exposure to smoking. | 22857644 | 2012 |
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0.070 | GeneticVariation | BEFREE | The overall current literature on hOGG1 Ser326Cys polymorphism and the risk of bladder cancer suggests no statistically significant association between the two. | 22156293 | 2012 |
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0.070 | GeneticVariation | BEFREE | We undertook a case-control study of 212 urothelial bladder cancer (UBC) cases and 250 controls to investigate the association between OGG1 (C1245G rs1052133), XRCC3 (C18067T, rs861539) and XRCC7 (G6721T, rs7003908) polymorphisms and bladder cancer susceptibility by PCR-RFLP and the ARMS method. | 19815090 | 2010 |
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0.070 | GeneticVariation | BEFREE | Consistent with the above findings, we found that the ADPRT V762A was only significantly involved in bladder cancer</span> risk in never smokers and the OGG1 S326C was only significantly involved in ever smokers. | 17220334 | 2007 |