|
rs1799793
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Among four DNA repair gene polymorphisms, the OGG1 326 Ser/Cys and XPD 312 Asp/Asn heterozygous genotypes might be recognized as potential genetic markers modifying susceptibility to bladder cancer in Belarus.
|
25089939 |
2014 |
|
rs1799793
|
|
|
0.080 |
GeneticVariation |
BEFREE |
For ERCC2 Asp312Asn, individuals with the Asn allele were associated with a 1.29-fold (95 % CI=1.13-1.48) increased risk of bladder cancer.
|
24504678 |
2014 |
|
rs1799793
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Overall, the variant allele of Asp312Asn polymorphism was associated with an increased risk of bladder cancer (Asn/Asn vs. Asp/Asp: OR = 1.51, 95% CI = 1.19-1.91; Asp/Asn vs. Asp/Asp: OR = 1.23, 95% CI = 1.12-1.35; recessive model: OR = 1.33, 95% CI = 1.10-1.61; dominant model: OR = 1.32, 95% CI = 1.14-1.52; and allele comparing: OR = 1.26, 95% CI = 1.11-1.42).
|
24347488 |
2014 |
|
rs1799793
|
|
|
0.080 |
GeneticVariation |
BEFREE |
These associations were: two SNPs rs1799793 and rs13181 in the ERCC2 gene and lung cancer (recessive model) and rs1805794 in the NBN gene and bladder cancer (dominant model).
|
21864546 |
2012 |
|
rs1799793
|
|
|
0.080 |
GeneticVariation |
BEFREE |
This meta-analysis suggested that the XPD Asp312Asn but not Lys751Gln polymorphism may be more genetically susceptible to bladder cancer development.
|
19492231 |
2009 |
|
rs1799793
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Polymorphic variants of XPD, at codon 312 (rs1799793), 751 (rs13181) and promoter-114 (rs3810366), were chosen to be studied for their association with bladder cancer susceptibility in a central Taiwanese population.
|
19846926 |
2009 |
|
rs1799793
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Subtle but significant cancer risk was observed for the XPD Asp 312 Asn polymorphism in bladder cancer (for Asp/Asn versus Asp/Asp: OR, 1.24; 95% CI, 1.06-1.46).
|
18349268 |
2008 |
|
rs1799793
|
|
|
0.080 |
GeneticVariation |
BEFREE |
In multifactor dimensionality reduction (MDR) analysis, the five-factor model including smoking, CCNH V270A, ERCC6 M1097V, RAD23B A249V and XPD D312N had the best ability to predict bladder cancer risk.
|
17728339 |
2007 |