rs1217691063
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Quantitative assessment of the association between MHTFR C677T (rs1801133, Ala222Val) polymorphism and susceptibility to bladder cancer.
|
23773402 |
2013 |
rs1217691063
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Results from the current update analysis suggested that the C677T and A1298C polymorphisms in the MTHFR gene were associated with BC risk and disease progression.
|
23578207 |
2013 |
rs1217691063
|
|
|
0.090 |
GeneticVariation |
BEFREE |
The results from the current update analysis suggest that C677T and A1298C polymorphisms in the MTHFR gene are associated with bladder cancer risk and prognosis.
|
22296361 |
2011 |
rs1217691063
|
|
|
0.090 |
GeneticVariation |
BEFREE |
The MTHFR gene C677T and A1298C polymorphisms were associated with an increased risk of bladder cancer in our population (For the MTHFR gene C677T polymorphism and A1298C polymorphism; p=0.036<0.05; p=0.278>0.05 respectively).
|
22126575 |
2011 |
rs1217691063
|
|
|
0.090 |
GeneticVariation |
BEFREE |
In this study, it was hypothesized that MTHFR (C677T and A1298C) polymorphisms would be associated with bladder cancer and also with hypermethylation of the promoter of the Ras association domain family 1A (RASSF1A) gene.
|
20146887 |
2010 |
rs1217691063
|
|
|
0.090 |
GeneticVariation |
BEFREE |
We hypothesized that the MTHFR C677T, A1298C, and MS A2756G polymorphisms are associated with risk of bladder cancer.
|
18815869 |
2009 |
rs1217691063
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Assuming a very low prior probability of 0.000001, similar to a probability assumed for a randomly selected single-nucleotide polymorphism in a genome-wide association study, and statistical power to detect an OR of 1.5, 4 associations were considered noteworthy as denoted by an FPRP value <0.2: GSTM1 null and bladder cancer (OR, 1.5; 95% CI, 1.3-1.6; P = 1.9 x 10(-14)), NAT2 slow acetylator and bladder cancer (OR, 1.46; 95% CI, 1.26-1.68; P = 2.5 x 10(-7)), MTHFR C677T and gastric cancer (OR, 1.52; 95% CI, 1.31-1.77; P = 4.9 x 10(-8)), and GSTM1 null and acute leukemia (OR, 1.20; 95% CI, 1.14-1.25; P = 8.6 x 10(-15)).
|
18505952 |
2008 |
rs1217691063
|
|
|
0.090 |
GeneticVariation |
BEFREE |
While the isolated polymorphism C677T did not appear to influence bladder cancer susceptibility, results suggest that it might act with an additive contribution determined by variation at MTHFR A1298C.
|
17574963 |
2007 |
rs1217691063
|
|
|
0.090 |
GeneticVariation |
BEFREE |
To clarify the role of MTHFR polymorphisms on bladder cancer risk, we genotyped MTHFR 677C > T and MTHFR 1298A > C in a population-based study of bladder cancer of 352 patients and 551 controls from New Hampshire, USA.
|
16217917 |
2005 |