|
rs55770810
|
|
|
0.810 |
GeneticVariation |
UNIPROT |
Risk assessment, genetic counseling, and genetic testing for BRCA-related cancer in women: U.S. Preventive Services Task Force recommendation statement.
|
24366376 |
2014 |
|
rs55770810
|
|
|
0.810 |
GeneticVariation |
BEFREE |
Measures of genetic risk (report of family history, segregation) were assessed for 68 BRCA1 c.5096G>A p.Arg1699Gln (R1699Q) families recruited through family cancer clinics, comparing results with 34 families carrying the previously classified pathogenic BRCA1 c.5095C>T p.Arg1699Trp (R1699W) mutation at the same residue, and to 243 breast cancer families with no BRCA1 pathogenic mutation (BRCA-X).
|
22889855 |
2012 |
|
rs200928781
|
|
|
0.810 |
GeneticVariation |
UNIPROT |
A recurrent CHEK2 p.H371Y mutation is associated with breast cancer risk in Chinese women.
|
21618645 |
2011 |
|
rs200928781
|
|
G |
0.810 |
GeneticVariation |
CLINVAR |
CHEK2 contribution to hereditary breast cancer in non-BRCA families.
|
22114986 |
2011 |
|
rs200928781
|
|
|
0.810 |
GeneticVariation |
UNIPROT |
The emerging landscape of breast cancer susceptibility.
|
18163131 |
2008 |
|
rs28897696
|
|
|
0.810 |
GeneticVariation |
UNIPROT |
The emerging landscape of breast cancer susceptibility.
|
18163131 |
2008 |
|
rs55770810
|
|
|
0.810 |
GeneticVariation |
UNIPROT |
The emerging landscape of breast cancer susceptibility.
|
18163131 |
2008 |
|
rs200928781
|
|
|
0.810 |
GeneticVariation |
UNIPROT |
Risk assessment and genetic counseling for hereditary breast and ovarian cancer: recommendations of the National Society of Genetic Counselors.
|
17508274 |
2007 |
|
rs28897696
|
|
|
0.810 |
GeneticVariation |
UNIPROT |
Risk assessment and genetic counseling for hereditary breast and ovarian cancer: recommendations of the National Society of Genetic Counselors.
|
17508274 |
2007 |
|
rs55770810
|
|
|
0.810 |
GeneticVariation |
UNIPROT |
Risk assessment and genetic counseling for hereditary breast and ovarian cancer: recommendations of the National Society of Genetic Counselors.
|
17508274 |
2007 |
|
rs200928781
|
|
|
0.810 |
GeneticVariation |
UNIPROT |
Genetic cancer risk assessment and counseling: recommendations of the national society of genetic counselors.
|
15604628 |
2004 |
|
rs28897696
|
|
|
0.810 |
GeneticVariation |
UNIPROT |
Genetic cancer risk assessment and counseling: recommendations of the national society of genetic counselors.
|
15604628 |
2004 |
|
rs55770810
|
|
|
0.810 |
GeneticVariation |
UNIPROT |
Genetic cancer risk assessment and counseling: recommendations of the national society of genetic counselors.
|
15604628 |
2004 |
|
rs200928781
|
|
|
0.810 |
GeneticVariation |
UNIPROT |
A CHEK2 genetic variant contributing to a substantial fraction of familial breast cancer.
|
12094328 |
2002 |
|
rs28897696
|
|
|
0.810 |
GeneticVariation |
BEFREE |
Two mutated forms of BRCA1, a missense (A1708E) and a nonsense (Y1853X) that have been identified in familial breast cancers, associated with Nmi and c-Myc but failed to suppress c-Myc-induced hTERT promoter activity.
|
11916966 |
2002 |
|
rs28897696
|
|
T |
0.810 |
CausalMutation |
CLINVAR |
|
|
|
|
rs28897759
|
|
T |
0.810 |
GeneticVariation |
CLINVAR |
|
|
|
|
rs28897759
|
|
|
0.810 |
GeneticVariation |
UNIPROT |
|
|
|
|
rs55770810
|
|
A |
0.810 |
CausalMutation |
CLINVAR |
|
|
|
|
rs121913279
|
|
|
0.800 |
GeneticVariation |
BEFREE |
We aimed to detect the tumor-derived free DNA in metastasis-free LNs in patients with breast cancers harboring the PIK3CA-H1047R mutation.
|
30805870 |
2019 |
|
rs121913279
|
|
|
0.800 |
GeneticVariation |
BEFREE |
In this study, we directly compared PIK3CA hotspot mutations (E545K, H1047R) in EpCAM-positive CTCs and paired plasma-ctDNA in breast cancer (BrCa).
|
31254443 |
2019 |
|
rs121913279
|
|
|
0.800 |
GeneticVariation |
BEFREE |
The hotspot mutation H1047R in the oncogenic PIK3CA gene is frequently detected in breast cancer and enhances the enzymatic activity of PI3K to activate AKT/mTOR signaling cascade.
|
30671946 |
2019 |
|
rs121913279
|
|
|
0.800 |
GeneticVariation |
BEFREE |
The aim of this study was to analyze the efficacy of PI3K/mTOR blockade in breast cancer brain metastases models.<b>Experimental Design:</b> The efficacy of GDC-0084 was evaluated in <i>PIK3CA</i>-mutant and <i>PIK3CA</i> wild-type breast cancer cell lines and the isogenic pairs of <i>PIK3CA</i> wild-type and mutant (H1047R/+) MCF10A cells <i>in vitro</i>.
|
30796030 |
2019 |
|
rs2046210
|
|
|
0.800 |
GeneticVariation |
BEFREE |
In summary, our findings suggested that the rs2046210 polymorphism may serve as a potential genetic biomarker of BC in both Asians and Caucasians.
|
30693664 |
2019 |
|
rs2981582
|
|
|
0.800 |
GeneticVariation |
BEFREE |
P21 Ser31Arg and FGFR2 rs2981582 Polymorphisms as Risk Factors for Early Onset of Breast Cancer in Yogyakarta, Indonesia.
|
31759353 |
2019 |