Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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0.740 | GeneticVariation | BEFREE | This meta-analysis of case-control studies provides strong evidence that fibroblast growth factor 2 (FGFR2; rs11200014, rs2981579, and rs1219648) polymorphisms are significantly associated with the BC risk. | 29390357 | 2017 |
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A | 0.740 | GeneticVariation | GWASDB | Large-scale genotyping identifies 41 new loci associated with breast cancer risk. | 23535729 | 2013 |
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0.740 | GeneticVariation | BEFREE | Four SNPs mapped to 10q26.13/FGFR2 were associated with increased breast cancer risk via an additive model with per-allelic risks (95 % CI) of 1.26 (1.12-1.43) at rs1219648, 1.22 (1.07-1.38) at rs2981582, 1.21 (1.07-1.36) at rs2981579, and 1.18 (1.04-1.35) at rs11200014. | 22965832 | 2012 |
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0.740 | GeneticVariation | BEFREE | A dose-dependent association was observed between the risk of breast cancer and the genetic risk score, which was an aggregate measure of alleles in seven selected variants, namely FGFR2-rs2981579, TOX3/TNRC9-rs3803662, C6orf97-rs2046210, 8q24-rs13281615, SLC4A7-rs4973768, LSP1-rs38137198, and CASP8-rs10931936. | 22160591 | 2012 |
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0.740 | GeneticVariation | BEFREE | Results from the current meta-analysis indicates that three novel functional polymorphisms (rs11200014, rs2981579, and rs2981578) in the promoter of FGFR2 gene are associated with breast cancer susceptibility and might be a potential biomarkers for breast cancer risk. | 23124475 | 2012 |
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A | 0.740 | GeneticVariation | GWASDB | Genome-wide association study identifies five new breast cancer susceptibility loci. | 20453838 | 2010 |
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T | 0.740 | GeneticVariation | GWASDB | A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1). | 19330030 | 2009 |