Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1136410
rs1136410
0.060 GeneticVariation BEFREE No association was detected between rs1136410 and susceptibility to BC among studied groups. 31288058

2019

dbSNP: rs1136410
rs1136410
0.060 GeneticVariation BEFREE There was no evidence to suggest that rs25489, rs1799782, rs1130409, rs1805414 and rs1136410 were associated with breast cancer risk. 29662639

2018

dbSNP: rs1136410
rs1136410
0.060 GeneticVariation BEFREE We aimed to explore the modification effects of PARP1 rs1136410 and ESR1 rs2234693 on the association between passive smoking and breast cancer risk among pre- and post-menopausal women. 23644255

2013

dbSNP: rs1136410
rs1136410
0.060 GeneticVariation BEFREE Taken together, this the first study that confirmed Val762Ala variant has functional effect and structural impact on the PARP1 and may play an important role in breast cancer progression in Saudi population. 24392019

2013

dbSNP: rs1136410
rs1136410
0.060 GeneticVariation BEFREE This meta-analysis indicates that ADPRT Val762Ala and APE1 Asp148Glu polymorphisms are not associated with increased breast cancer risk. 23272074

2012

dbSNP: rs1136410
rs1136410
0.060 GeneticVariation BEFREE Using data/samples collected from the first 752 Caucasians and 141 African-Americans in an ongoing case-control study, we examined the association between breast cancer risk and 18 non-synonymous single-nucleotide polymorphisms (nsSNPs) in four DNA repair pathways-(i) base excision repair: ADPRT V762A, APE1 D148E, XRCC1 R194W/R280H/R399Q and POLD1 R119H; (ii) nucleotide excision repair: ERCC2 D312N/K751Q, ERCC4 R415Q, ERCC5 D1104H and XPC A499V/K939Q; (iii) mismatch repair: MLH1 I219V, MSH3 R940Q/T1036A and MSH6 G39E and (iv) double-strand break repair: NBS1 E185Q and XRCC3 T241M. 18701435

2008

dbSNP: rs1805414
rs1805414
0.030 GeneticVariation BEFREE There was no evidence to suggest that rs25489, rs1799782, rs1130409, rs1805414 and rs1136410 were associated with breast cancer risk. 29662639

2018

dbSNP: rs1805414
rs1805414
0.030 GeneticVariation BEFREE In conclusion PARP1 rs1805414 SNP polymorphisms may be involved in the etiology of breast cancer</span> in the Saudi population. 23803078

2013

dbSNP: rs1805414
rs1805414
0.030 GeneticVariation BEFREE The present study implies that genetic variants of PARP-1 may contribute to breast cancerogenesis and that PARP-1 htSNP c.852T>C (Ala284Ala) may influence hormonal therapy of breast cancer. 17560163

2007

dbSNP: rs4653734
rs4653734
0.010 GeneticVariation BEFREE The current study suggests that rs907187 and rs4653734 have remarkable associations with BC risk among Iranian women. 31288058

2019

dbSNP: rs907187
rs907187
0.010 GeneticVariation BEFREE The current study suggests that rs907187 and rs4653734 have remarkable associations with BC risk among Iranian women. 31288058

2019

dbSNP: rs1805404
rs1805404
0.010 GeneticVariation BEFREE In contrast, PARP1 rs1805404 did not show any significant association in overall in breast cancer samples when compared to healthy controls. 23803078

2013

dbSNP: rs8679
rs8679
0.010 GeneticVariation BEFREE The PARP-1 SNP rs8679 was also genotyped in a breast cancer case-control series (257 cases and 512 controls). 22166496

2012

dbSNP: rs139399785
rs139399785
0.010 GeneticVariation BEFREE Twenty rare genetic variants of PARP-1, including c.1148C>A (Ser383Tyr), c.1354C>A (Arg452Arg), c.2819A>G (Lys940Arg) were detected in nine (10.8%) breast cancers of these patients. 17560163

2007

dbSNP: rs2230484
rs2230484
0.010 GeneticVariation BEFREE Additional studies in other cohorts and other populations are however needed to further evaluate the implication of the Pro377Ser missense variant with regard to breast cancer susceptibility. 17943227

2007

dbSNP: rs3219145
rs3219145
0.010 GeneticVariation BEFREE Twenty rare genetic variants of PARP-1, including c.1148C>A (Ser383Tyr), c.1354C>A (Arg452Arg), c.2819A>G (Lys940Arg) were detected in nine (10.8%) breast cancers of these patients. 17560163

2007