|
rs1800896
|
|
|
0.030 |
GeneticVariation |
BEFREE |
IL-10 rs1800896 gene polymorphism was associated with post-bronchiolitis asthma at 11-13 years of age in children hospitalised for bronchiolitis at less than six months of age.
|
31074014 |
2019 |
|
rs1800896
|
|
|
0.030 |
GeneticVariation |
BEFREE |
IL10 rs1800890 and rs1800896 polymorphisms differed between infants with rhinovirus bronchiolitis and controls, but not between infants with respiratory syncytial virus bronchiolitis and controls.
|
29802545 |
2018 |
|
rs1800896
|
|
|
0.030 |
GeneticVariation |
BEFREE |
IL-10 polymorphisms at rs1800871, rs1800872, rs1800890, and rs1800896 seem to be associated with elevated allergies and/or recurrent wheezing risk in later childhood, after early-life bronchiolitis.Pediatr Pulmonol.2017;52:14-20.© 2016 Wiley Periodicals, Inc.
|
27228545 |
2017 |
|
rs4986790
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The aim was to study the association between the TLR4 Asp299Gly polymorphism and the susceptibility to severe RSV bronchiolitis in infants.
|
20575099 |
2010 |
|
rs4986790
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The presence of TLR4 mutations (Asp299Gly and Thr399Ile) were associated with severe RSV bronchiolitis and were significantly over-represented in groups II and III.
|
16542364 |
2006 |
|
rs4986790
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Each of the TLR4 mutations, either alone or in cosegregation, were associated with severe RSV bronchiolitis: the Asp299Gly and Thr399Ile mutations were significantly overrepresented in group I, compared with groups II and III.
|
15143473 |
2004 |
|
rs12979860
|
|
|
0.020 |
GeneticVariation |
BEFREE |
SNPs rs12979860 and rs8099917 correlate with the severity of bronchiolitis and display a sex bias, where GG rs8099917 and TT rs12979860 genotypes are associated with a mild disease in girls but not in boys.
|
31645053 |
2020 |
|
rs8099917
|
|
|
0.020 |
GeneticVariation |
BEFREE |
SNPs rs12979860 and rs8099917 correlate with the severity of bronchiolitis and display a sex bias, where GG rs8099917 and TT rs12979860 genotypes are associated with a mild disease in girls but not in boys.
|
31645053 |
2020 |
|
rs1800890
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Infants with rhinovirus bronchiolitis had the IL10 rs1800890 variant AT or TT genotype less often (18.2%) than controls (63.3%, P = 0.03), and likewise, had the IL10 rs1800896 variant AG or GG genotype less often (27.3%) than controls (65.5%, P = 0.009).
|
29802545 |
2018 |
|
rs2275913
|
|
|
0.020 |
GeneticVariation |
BEFREE |
IL-17A gene polymorphism rs2275913 is associated with the development of asthma after bronchiolitis in infancy.
|
28647382 |
2018 |
|
rs1800890
|
|
|
0.020 |
GeneticVariation |
BEFREE |
IL-10 polymorphisms at rs1800871, rs1800872, rs1800890, and rs1800896 seem to be associated with elevated allergies and/or recurrent wheezing risk in later childhood, after early-life bronchiolitis.Pediatr Pulmonol.2017;52:14-20.© 2016 Wiley Periodicals, Inc.
|
27228545 |
2017 |
|
rs12979860
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Overall our results indicate that both IL28B SNPs had no impact on the clinical course of bronchiolitis with the only exception of the IL28B rs12979860 SNP which increased the risk of hospitalization for bronchiolitis at early age.
|
22374338 |
2012 |
|
rs8099917
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The aim of this study was to determine whether the known rs12979860 and rs8099917 single nucleotide polymorphisms (SNPs) in interleukin (IL)28B region, influence clinical features and natural history of bronchiolitis.
|
22374338 |
2012 |
|
rs2275913
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The distribution of SNP rs2275913 in bronchiolitis was marginally statistically different with controls and demonstrated a tendency close to that in asthma.
|
20437253 |
2010 |
|
rs4986791
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The presence of TLR4 mutations (Asp299Gly and Thr399Ile) were associated with severe RSV bronchiolitis and were significantly over-represented in groups II and III.
|
16542364 |
2006 |
|
rs4986791
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Each of the TLR4 mutations, either alone or in cosegregation, were associated with severe RSV bronchiolitis: the Asp299Gly and Thr399Ile mutations were significantly overrepresented in group I, compared with groups II and III.
|
15143473 |
2004 |
|
rs601338
|
|
|
0.010 |
GeneticVariation |
BEFREE |
For FUT2 SNP rs601338, the risk ratios for ≥1 bout of diarrhea during ages 6-12 months and ages 12-24 months per additional risk (G) allele were 1.23 (95% confidence interval [CI], 1.08-1.4; P = .002) and 1.41 (95% CI, 1.24-1.61; P = 1.7 × 10-7), respectively; the risk ratio for ≥1 diagnosis of a lower respiratory illness (ie, pneumonia or bronchiolitis) during ages 12-24 months per additional G allele was 2.66 (95% CI, 1.64-4.3; P = .00007).
|
30376117 |
2019 |
|
rs1800871
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The objective of this study was to evaluate the associations between IL10 single nucleotide polymorphisms (SNPs) at rs1800890 (- 3575A/T), rs1800871 (- 819C/T) or rs1800872 (- 592C/A) either alone or combined with the SNP at rs1800896 (- 1082G/A), and the etiology and severity of infant bronchiolitis.
|
29802545 |
2018 |
|
rs1800872
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The objective of this study was to evaluate the associations between IL10 single nucleotide polymorphisms (SNPs) at rs1800890 (- 3575A/T), rs1800871 (- 819C/T) or rs1800872 (- 592C/A) either alone or combined with the SNP at rs1800896 (- 1082G/A), and the etiology and severity of infant bronchiolitis.
|
29802545 |
2018 |
|
rs187084
|
|
|
0.010 |
GeneticVariation |
BEFREE |
TLR9 rs187084 gene polymorphism may be associated with post-bronchiolitis wheezing, and TLR10 rs4129009 gene polymorphism may be associated with atopy.
|
27498757 |
2016 |
|
rs2407992
|
|
|
0.010 |
GeneticVariation |
BEFREE |
There were no significant associations between the genotypes or allele frequencies of TLR7 rs179008, TLR8 rs2407992, TLR9 rs187084 or TLR10 rs4129009 polymorphisms and clinical characteristics or the severity of bronchiolitis during hospitalization.
|
27498757 |
2016 |
|
rs4129009
|
|
|
0.010 |
GeneticVariation |
BEFREE |
There were no significant associations between the genotypes or allele frequencies of TLR7 rs179008, TLR8 rs2407992, TLR9 rs187084 or TLR10 rs4129009 polymorphisms and clinical characteristics or the severity of bronchiolitis during hospitalization.
|
27498757 |
2016 |
|
rs11650680
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We conducted a case-control study examining the associations between ORMDL3 polymorphisms (rs7216389, rs12603332, and rs11650680) and bronchiolitis susceptibility/viral findings among 247 infant bronchiolitis cases and 190 healthy controls.
|
26782568 |
2015 |
|
rs12603332
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We conducted a case-control study examining the associations between ORMDL3 polymorphisms (rs7216389, rs12603332, and rs11650680) and bronchiolitis susceptibility/viral findings among 247 infant bronchiolitis cases and 190 healthy controls.
|
26782568 |
2015 |
|
rs1800888
|
|
|
0.010 |
GeneticVariation |
BEFREE |
One of the variants was a highly functional nonsynonymous variant in ADRB2 (rs1800888), which was also nominally associated with asthma (p = 0.027) and active asthma (p = 0.013) among European Americans with severe RSV bronchiolitis without including the ESP.
|
26587832 |
2015 |