Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs200085146
rs200085146
0.700 GeneticVariation UNIPROT

dbSNP: rs748434421
rs748434421
0.700 GeneticVariation UNIPROT

dbSNP: rs774057024
rs774057024
0.700 GeneticVariation UNIPROT

dbSNP: rs1800566
rs1800566
0.100 GeneticVariation BEFREE "NQO1 Gene C609T Polymorphism (dbSNP: rs1800566) and Digestive Tract Cancer Risk: A Meta-Analysis." 29652514

2019

dbSNP: rs2585428
rs2585428
0.030 GeneticVariation BEFREE <b>Aim:</b> rs2585428 and rs4809960 polymorphisms were significantly associated with overall cancer risk, but there is no evidence regarding the overall colorectal cancer (CRC) risk. 31802707

2020

dbSNP: rs4809960
rs4809960
0.030 GeneticVariation BEFREE <b>Aim:</b> rs2585428 and rs4809960 polymorphisms were significantly associated with overall cancer risk, but there is no evidence regarding the overall colorectal cancer (CRC) risk. 31802707

2020

dbSNP: rs7799039
rs7799039
0.010 GeneticVariation BEFREE <b>Conclusion:</b> In conclusion, our study suggests that the <i>LEP</i> rs7799039 G>A polymorphism might contribute to the development of cancer. 31114233

2019

dbSNP: rs1138272
rs1138272
0.040 GeneticVariation BEFREE <b>Conclusion:</b> The TT genotype of the <i>GSTP1</i> rs1138272 polymorphism is likely related to the susceptibility to overall cancer in the Asian and African populations and, specifically, "Colorectal" and "Head and neck" cancers in the Caucasian population. 30740061

2018

dbSNP: rs80357086
rs80357086
0.010 GeneticVariation BEFREE <b>Conclusions:</b> A high proportion of Japanese HBOC patients showed the <i>BRCA1</i> L63X mutation, and the clinical characteristics of breast cancer in patients with this mutation might differ from those in patients with other <i>BRCA1</i> or <i>BRCA2</i> mutations, in terms of the subtype and nuclear grade of the resultant cancer. 31143373

2019

dbSNP: rs11614913
rs11614913
0.100 GeneticVariation BEFREE <b>Conclusions:</b> The present meta-analysis suggests that mir-196a-2 rs11614913 may contribute to the risk of cancer especially in Asians. 30930933

2019

dbSNP: rs367597251
rs367597251
0.010 GeneticVariation BEFREE <b>Methods:</b> Osteosarcoma cancer cell line MG-63 was transfected with Ras gene with G12V and Y40C site mutation. 31126199

2019

dbSNP: rs11187842
rs11187842
0.010 GeneticVariation BEFREE <b>Objectives:</b> In the current study, we conducted a meta-analysis to more accurately evaluate the relationships between <i>PLCE1</i> (rs2274223, rs3765524, rs753724, rs11187842, and rs7922612) single nucleotide polymorphisms (SNPs) and risk for different types of cancer. 30619753

2018

dbSNP: rs7922612
rs7922612
0.010 GeneticVariation BEFREE <b>Objectives:</b> In the current study, we conducted a meta-analysis to more accurately evaluate the relationships between <i>PLCE1</i> (rs2274223, rs3765524, rs753724, rs11187842, and rs7922612) single nucleotide polymorphisms (SNPs) and risk for different types of cancer. 30619753

2018

dbSNP: rs9344
rs9344
0.010 GeneticVariation BEFREE <b>Results:</b> Overall, the cumulative findings demonstrated that <i>CCND1</i> polymorphism (rs9344) was not significantly associated with cancer risk in all the genetic models studied (dominant model: GG vs GA+AA: OR (95%CI) = 0.81 (0.60-1.09), <i>P</i>=0.17; recessive model: GG+GA vs AA: OR (95%CI) = 1.23 (0.96-1.59), <i>P</i>=0.11; co-dominant model: <b>GG vs AA: OR (95%CI) = 1.35 (0.93-1.97), <i>P</i>=0.12;</b> co-dominant model: <b>(GG vs GA: OR (95%CI) = 1.16 (0.85-1.59), <i>P</i>=0.34</b>; allelic model: A vs G: OR (95%CI) = 1.20 (1.14-2.85), <i>P</i>=0.23; allelic model: G vs A: OR (95%CI) = 0.83 (0.62-1.12), <i>P</i>=0.23). 30361291

2018

dbSNP: rs402710
rs402710
0.020 GeneticVariation BEFREE <i>CLPTM1L</i> gene rs402710 (C > T) and rs401681 (C > T) polymorphisms associate with decreased cancer risk: a meta-analysis. 29254260

2017

dbSNP: rs401681
rs401681
0.100 GeneticVariation BEFREE <i>CLPTM1L</i> gene rs402710 and rs401681 polymorphisms thus have a protective association with various types of cancer, especially lung cancer among Asians. 29254260

2017

dbSNP: rs2736098
rs2736098
0.100 GeneticVariation BEFREE <i>TERT</i> rs2736098 (Ex2-659G>A) polymorphism and cancer susceptibility: evidence from a comprehensive meta-analysis. 29221218

2017

dbSNP: rs4975616
rs4975616
0.010 GeneticVariation BEFREE 3'UTR variant of HADH, rs221347 and rs4975616, located within known cancer risk locus 5p15.33, were specific to risk of laryngeal cancer. 28582492

2017

dbSNP: rs3746444
rs3746444
0.100 GeneticVariation BEFREE 35, 95% CI: 1.09-1.67), and rs3746444 was associated with liver cancer in the subgroup of cance</span>r types. 23725137

2013

dbSNP: rs1217691063
rs1217691063
0.100 GeneticVariation BEFREE Cancer risk may be increased in individuals with the homozygous genotype for the MTHFR 677C-->T polymorphism who have low status of methyl-related nutrients including folate. 14608109

2003

dbSNP: rs121912664
rs121912664
0.100 GeneticVariation BEFREE Because protocols for cancer-risk management in Li-Fraumeni or related syndromes are debatable, extreme care should prevail in predictive testing of children for R337H. 19717094

2009

dbSNP: rs1443496641
rs1443496641
0.010 GeneticVariation BEFREE Cancer patients with severe antimetabolite toxicity were evaluated for methylenetetrahydrofolate reductase (MTHFR) gene C667T, thymidilate synthase (TS) gene 5' UTR variable number of tandem repeats (VNTR), dihydroprymidine dehydrogenase (DPYD) gene IVS14+1G/A, Xeroderma pigmentosum (XPD) gene Lys751Gln and X-ray repair cross-complementing group 1 (XRCC1) gene Arg399Gln polymorphisms. 22799365

2012

dbSNP: rs6220
rs6220
0.020 GeneticVariation BEFREE Cancer-specific survival was significantly associated with the CA repeat polymorphism, rs12423791, and rs6220 (P = 0.013, 0.014, and 0.014, respectively). 23530598

2013

dbSNP: rs12423791
rs12423791
0.010 GeneticVariation BEFREE When the sum of the risk genetic factors in each LD block (19-repeat allele, C allele of rs12423791, or C-T haplotype) was considered, patients with all the risk factors had significantly shorter cancer specific-survival than those with 0-2 risk factors (P = 0.0003). 23530598

2013

dbSNP: rs121913500
rs121913500
0.060 GeneticVariation BEFREE Cancer-associated isocitrate dehydrogenase 1 (IDH1) R132H mutation and d-2-hydroxyglutarate stimulate glutamine metabolism under hypoxia. 24986863

2014