In addition, overall, there was no significant association between <i>FTO</i> rs1477196 variant and cancer risk regardless of adjustment for body mass index.
The homocysteine level was not associated with either MTHFR C677T or A1298C, nor with FTO rs1477196, but was inversely correlated with folate status in cancer cases (p<0.0001) and tended to be higher in patients with the MTHFR 677TT genotype.