| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
0.070 | GeneticVariation | BEFREE | The most common polymorphism in SULT1A1 (Arg213His) has an important functional impact by affecting the capacity to sulfate diverse substrates and numerous case-control studies have shown associations between SULT1A1 variants and susceptibility to different malignancies. | 26892733 | 2016 |
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|
0.070 | GeneticVariation | BEFREE | The present meta-analysis suggests that SULT1A1 Arg213His polymorphism plays an important role in carcinogenesis, which may be a genetic factor affecting individual susceptibility to UADT cancer. | 25225888 | 2014 |
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|
0.070 | GeneticVariation | BEFREE | The common genetic polymorphism for SULT1A1 is Arg213His</span> polymorphism, which may affect the sulfation process of various environmental carcinogens and thus is suggested to be related to susceptibility of several cancers. | 21670965 | 2012 |
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|
0.070 | GeneticVariation | BEFREE | Statistical analyses of histological types of lung cancer in comparison with the control individuals indicated a significant difference between SULT1A1 Arg(213)His polymorphism and SCC (p = 0.027) and other types of cancer (p = 0.037), except SMCC (p = 0.854). | 19350537 | 2009 |
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|
0.070 | GeneticVariation | BEFREE | Case-control study and meta-analysis of SULT1A1 Arg213His polymorphism for gene, ethnicity and environment interaction for cancer risk. | 18854828 | 2008 |
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|
0.070 | GeneticVariation | BEFREE | A functional polymorphism in the SULT1A1 gene, leading to an Arg213His substitution (SULT1A1*2), is thought to confer susceptibility to various types of cancer. | 18006944 | 2007 |
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|
0.070 | GeneticVariation | BEFREE | Statistically significant associations were observed between the SULT1A1 genotype (Arg213His) and age, obesity and certain neoplasias (mammary, pulmonary, esophageal and urothelial cancer). | 14600802 | 2004 |