The results suggested that there is a strong association between rs41</span>43815 C > G and the cancer risks (G vs. C: OR = 1.386, 95% CI: 1.132-1.696, p = 0.002; GG vs. CG + CC: OR = 1.843 95% CI: 1.300-2.613, p = 0.002; GG + CG vs. CC: OR = 1.280, 95% CI: 1.040-1.576, p = 0.020).
In conclusions, the results of this meta-analysis have revealed an association between <i>PD-1</i> rs2227981, rs11568821, rs7421861, as well as <i>PD-L1</i> rs4143815 polymorphisms and overall cancer susceptibility.