Gene: ESR1 ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2234693
rs2234693
ESR1
0.020 GeneticVariation BEFREE Our data suggest that the ESR1 (rs2234693 and rs9340799) and the ESR2 (rs1255998 and rs944050) polymorphisms may be associated with an increased risk of developing endometrial cancer. 19438492

2009
dbSNP: rs9340799
rs9340799
ESR1
0.020 GeneticVariation BEFREE Our data suggest that the ESR1 (rs2234693 and rs9340799) and the ESR2 (rs1255998 and rs944050) polymorphisms may be associated with an increased risk of developing endometrial cancer. 19438492

2009
dbSNP: rs2234693
rs2234693
ESR1
0.020 GeneticVariation BEFREE We found an association between rs2234670, rs2234693, as well as rs9340799, markers in strong linkage disequilibrium (LD), and endometrial cancer risk. 18990228

2008
dbSNP: rs9340799
rs9340799
ESR1
0.020 GeneticVariation BEFREE We found an association between rs2234670, rs2234693, as well as rs9340799, markers in strong linkage disequilibrium (LD), and endometrial cancer risk. 18990228

2008
dbSNP: rs79575945
rs79575945
ESR1
0.010 GeneticVariation BEFREE There was evidence of an EC risk signal located at a potential alternative promoter of the ESR1 gene (lead SNP rs79575945, P=1.86×10(-5)), which was stronger for cancers of endometrioid subtype (P=3.76×10(-6)). 26330482

2015
dbSNP: rs3020314
rs3020314
ESR1
0.010 GeneticVariation BEFREE The current meta-analysis suggests that PvuII (C>T) and rs3020314 (C>T) polymorphisms may be risk factors for endometrial cancer, especially among Caucasian populations. 23593326

2013
dbSNP: rs149308960
rs149308960
ESR1
0.010 GeneticVariation BEFREE The CYP1B1 and ERalpha genes may play a role in endometrial cancer and the Arg48Gly (142C > G) -CYP1B1 and 975C > G-ERalpha polymorphisms may be considered as independent, early diagnostic markers in this disease. 20492382

2010
dbSNP: rs1801132
rs1801132
ESR1
0.010 GeneticVariation BEFREE The CYP1B1 and ERalpha genes may play a role in endometrial cancer and the Arg48Gly (142C > G) -CYP1B1 and 975C > G-ERalpha polymorphisms may be considered as independent, early diagnostic markers in this disease. 20492382

2010