Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1042522
rs1042522
0.040 GeneticVariation BEFREE This meta-analysis indicated that TP53 Arg72Pro polymorphism probably had little association with skin cancer susceptibility mainly in Caucasians. 24260330

2013

dbSNP: rs1131691014
rs1131691014
0.040 GeneticVariation BEFREE This meta-analysis indicated that TP53 Arg72Pro polymorphism probably had little association with skin cancer susceptibility mainly in Caucasians. 24260330

2013

dbSNP: rs878854066
rs878854066
0.040 GeneticVariation BEFREE This meta-analysis indicated that TP53 Arg72Pro polymorphism probably had little association with skin cancer susceptibility mainly in Caucasians. 24260330

2013

dbSNP: rs1042522
rs1042522
0.040 GeneticVariation BEFREE In conclusion, this meta-analysis suggests that the TP53 Arg72Pro polymorphism may have little involvement in skin cancer susceptibility. 20861852

2011

dbSNP: rs1131691014
rs1131691014
0.040 GeneticVariation BEFREE In conclusion, this meta-analysis suggests that the TP53 Arg72Pro polymorphism may have little involvement in skin cancer susceptibility. 20861852

2011

dbSNP: rs878854066
rs878854066
0.040 GeneticVariation BEFREE In conclusion, this meta-analysis suggests that the TP53 Arg72Pro polymorphism may have little involvement in skin cancer susceptibility. 20861852

2011

dbSNP: rs1042522
rs1042522
0.040 GeneticVariation BEFREE We evaluated the effect of MDM2 SNP309 and its interaction with the p53 Arg72Pro polymorphism on pigmentary phenotypes and skin cancer risk in a nested case-control study within the Nurses' Health Study (NHS) among 219 melanoma cases, 286 squamous cell carcinoma (SCC) cases, 300 basal cell carcinoma (BCC) cases, and 873 controls, and among controls from other studies. 18814047

2009

dbSNP: rs1131691014
rs1131691014
0.040 GeneticVariation BEFREE We evaluated the effect of MDM2 SNP309 and its interaction with the p53 Arg72Pro polymorphism on pigmentary phenotypes and skin cancer risk in a nested case-control study within the Nurses' Health Study (NHS) among 219 melanoma cases, 286 squamous cell carcinoma (SCC) cases, 300 basal cell carcinoma (BCC) cases, and 873 controls, and among controls from other studies. 18814047

2009

dbSNP: rs878854066
rs878854066
0.040 GeneticVariation BEFREE We evaluated the effect of MDM2 SNP309 and its interaction with the p53 Arg72Pro polymorphism on pigmentary phenotypes and skin cancer risk in a nested case-control study within the Nurses' Health Study (NHS) among 219 melanoma cases, 286 squamous cell carcinoma (SCC) cases, 300 basal cell carcinoma (BCC) cases, and 873 controls, and among controls from other studies. 18814047

2009

dbSNP: rs1042522
rs1042522
0.040 GeneticVariation BEFREE We evaluated the association of the Arg72Pro polymorphism with skin cancer risk among Caucasians in a nested case-control study within the Nurses' Health Study (NHS) (219 melanoma, 286 squamous cell carcinoma (SCC), and 300 basal cell carcinoma (BCC) and 874 controls). 16739124

2006

dbSNP: rs1131691014
rs1131691014
0.040 GeneticVariation BEFREE We evaluated the association of the Arg72Pro polymorphism with skin cancer risk among Caucasians in a nested case-control study within the Nurses' Health Study (NHS) (219 melanoma, 286 squamous cell carcinoma (SCC), and 300 basal cell carcinoma (BCC) and 874 controls). 16739124

2006

dbSNP: rs878854066
rs878854066
0.040 GeneticVariation BEFREE We evaluated the association of the Arg72Pro polymorphism with skin cancer risk among Caucasians in a nested case-control study within the Nurses' Health Study (NHS) (219 melanoma, 286 squamous cell carcinoma (SCC), and 300 basal cell carcinoma (BCC) and 874 controls). 16739124

2006

dbSNP: rs12203592
rs12203592
0.030 GeneticVariation BEFREE This meta-analysis indicates that the IL-6 gene -174G/C and IRF4 rs12203592</span> polymorphisms may be associated with an increased skin cancer risk. 26928068

2017

dbSNP: rs1799793
rs1799793
0.030 GeneticVariation BEFREE Furthermore, the ERCC2 Asp312Asn polymorphism is associated with bladder, esophageal, and gastric cancers, but not with breast, head and neck, lung, prostate, and skin cancers, and non-Hodgkin lymphoma. 28489582

2017

dbSNP: rs12203592
rs12203592
0.030 GeneticVariation BEFREE Our meta-analysis indicated that the r</span>s12203592 and rs872071 IRF4 gene polymorphisms are associated with individual susceptibility to skin cancer and haematological malignancies. 24906573

2014

dbSNP: rs1799793
rs1799793
0.030 GeneticVariation BEFREE For the XPD Asp312Asn polymorphism, no significant association with skin cancer risk was observed in overall or subgroup analyses. 25169498

2014

dbSNP: rs12203592
rs12203592
0.030 GeneticVariation BEFREE Along with two known pigmentation loci, MC1R and OCA2, the IRF4 rs12203592 T allele was associated with an increased risk of each type of skin cancer (P value, 6.6 × 10(-4) for melanoma, 7.0 × 10(-7) for SCC, and 0.04 for BCC). 21270109

2011

dbSNP: rs1799782
rs1799782
0.030 GeneticVariation BEFREE The Arg399Gln and Arg194Trp polymorphisms were not correlated with skin cancer risk when all studies were pooled into the meta-analysis under three genetic models. 22110224

2011

dbSNP: rs25487
rs25487
0.030 GeneticVariation BEFREE The Arg399Gln and Arg194Trp polymorphisms were not correlated with skin cancer risk when all studies were pooled into the meta-analysis under three genetic models. 22110224

2011

dbSNP: rs1799782
rs1799782
0.030 GeneticVariation BEFREE Our data suggest that the Arg194Trp and Arg399Gln polymorphisms may be differentially associated with skin cancer risk. 17355263

2007

dbSNP: rs25487
rs25487
0.030 GeneticVariation BEFREE Our data suggest that the Arg194Trp and Arg399Gln polymorphisms may be differentially associated with skin cancer risk. 17355263

2007

dbSNP: rs1799793
rs1799793
0.030 GeneticVariation BEFREE We assessed the associations between two common nonsynonymous polymorphisms (Asp312Asn and Lys751Gln) with skin cancer risk in a nested case-control study within the Nurses' Health Study (219 melanoma, 286 squamous cell carcinoma, 300 basal cell carcinoma, and 874 controls) along with exploratory analysis on the haplotype structure of the XPD gene. 15941969

2005

dbSNP: rs1799782
rs1799782
0.030 GeneticVariation BEFREE Our data suggest that the Arg194Trp and Arg399Gln polymorphisms may be differently associated with skin cancer risk according to exposure dose and skin cancer type. 15381933

2004

dbSNP: rs25487
rs25487
0.030 GeneticVariation BEFREE Our data suggest that the Arg194Trp and Arg399Gln polymorphisms may be differently associated with skin cancer risk according to exposure dose and skin cancer type. 15381933

2004

dbSNP: rs1217691063
rs1217691063
0.020 GeneticVariation BEFREE The data obtained from this meta-analysis suggest that the MTHFR 1298C allele is associated with increased skin cancer risk, particularly BCC; however, no association was observed between the MTHFR C677T polymorphism and skin cancer. 25306137

2015