rs137852986
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs180177135
|
|
G |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs532480170
|
|
T |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
rs80359180
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs75915166
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Analysis of DCIS by grade suggested that two independent SNPs at 11q13.3 near CCND1 were specific to low/intermediate grade DCIS (rs75915166, rs554219).
|
26884359 |
2016 |
rs1043994
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A total of 100 invasive ductal carcinoma (IDC) and 50 ductal carcinoma in situ (DCIS) patients and 100 usual ductal hyperplasia (UDH) controls were genotyped for the following Notch receptor single nucleotide polymorphisms (SNPs) using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry: Notch1, rs3124591; Notch2, rs11249433; Notch3, rs3815188, and rs1043994; and Notch4, rs367398, and rs520692.
|
25120811 |
2014 |
rs11249433
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A total of 100 invasive ductal carcinoma (IDC) and 50 ductal carcinoma in situ (DCIS) patients and 100 usual ductal hyperplasia (UDH) controls were genotyped for the following Notch receptor single nucleotide polymorphisms (SNPs) using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry: Notch1, rs3124591; Notch2, rs11249433; Notch3, rs3815188, and rs1043994; and Notch4, rs367398, and rs520692.
|
25120811 |
2014 |
rs3124591
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Furthermore, given the inconsistent associations between the rs3124591</span> variant and Notch1 expression in IDC and DCIS, this variant may affect breast cancer risk through mechanisms in the latter stage other than alterations in Notch1 protein expression.
|
25120811 |
2014 |
rs367398
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A total of 100 invasive ductal carcinoma (IDC) and 50 ductal carcinoma in situ (DCIS) patients and 100 usual ductal hyperplasia (UDH) controls were genotyped for the following Notch receptor single nucleotide polymorphisms (SNPs) using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry: Notch1, rs3124591; Notch2, rs11249433; Notch3, rs3815188, and rs1043994; and Notch4, rs367398, and rs520692.
|
25120811 |
2014 |
rs3815188
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A total of 100 invasive ductal carcinoma (IDC) and 50 ductal carcinoma in situ (DCIS) patients and 100 usual ductal hyperplasia (UDH) controls were genotyped for the following Notch receptor single nucleotide polymorphisms (SNPs) using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry: Notch1, rs3124591; Notch2, rs11249433; Notch3, rs3815188, and rs1043994; and Notch4, rs367398, and rs520692.
|
25120811 |
2014 |
rs520692
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A total of 100 invasive ductal carcinoma (IDC) and 50 ductal carcinoma in situ (DCIS) patients and 100 usual ductal hyperplasia (UDH) controls were genotyped for the following Notch receptor single nucleotide polymorphisms (SNPs) using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry: Notch1, rs3124591; Notch2, rs11249433; Notch3, rs3815188, and rs1043994; and Notch4, rs367398, and rs520692.
|
25120811 |
2014 |
rs10941679
|
|
|
0.010 |
GeneticVariation |
BEFREE |
For white Europeans, the per-allele OR associated with 5p12-rs10941679 was 1.11 (95% CI = 1.08-1.14, P = 7 × 10(-18)) for invasive breast cancer and 1.10 (95% CI = 1.01-1.21, P = 0.03) for DCIS.
|
21795498 |
2011 |
rs80358829
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The BRCA2 C5972T allele is a common variant in Poland that increases the risk of DCIS with micro-invasion.
|
16280055 |
2005 |