|
rs121913529
|
|
T |
0.790 |
CausalMutation |
CLINVAR |
BRAF and RAS mutations in human lung cancer and melanoma.
|
12460918 |
2002 |
|
rs121913529
|
|
G |
0.790 |
CausalMutation |
CLINVAR |
BRAF and RAS mutations in human lung cancer and melanoma.
|
12460918 |
2002 |
|
rs121913529
|
|
G |
0.790 |
CausalMutation |
CLINVAR |
KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib.
|
15696205 |
2005 |
|
rs121913529
|
|
A |
0.790 |
CausalMutation |
CLINVAR |
KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib.
|
15696205 |
2005 |
|
rs121913529
|
|
T |
0.790 |
CausalMutation |
CLINVAR |
KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib.
|
15696205 |
2005 |
|
rs121913529
|
|
T |
0.790 |
CausalMutation |
CLINVAR |
Somatic PTPN11 mutations in childhood acute myeloid leukaemia.
|
15842656 |
2005 |
|
rs121913529
|
|
T |
0.790 |
CausalMutation |
CLINVAR |
Spontaneous improvement of hematologic abnormalities in patients having juvenile myelomonocytic leukemia with specific RAS mutations.
|
17332249 |
2007 |
|
rs121913529
|
|
A |
0.790 |
CausalMutation |
CLINVAR |
Spontaneous improvement of hematologic abnormalities in patients having juvenile myelomonocytic leukemia with specific RAS mutations.
|
17332249 |
2007 |
|
rs121913529
|
|
A |
0.790 |
CausalMutation |
CLINVAR |
Cardio-facio-cutaneous and Noonan syndromes due to mutations in the RAS/MAPK signalling pathway: genotype-phenotype relationships and overlap with Costello syndrome.
|
17704260 |
2007 |
|
rs121913529
|
|
T |
0.790 |
CausalMutation |
CLINVAR |
Mutations of FLT3, NRAS, KRAS, and PTPN11 are frequent and possibly mutually exclusive in high hyperdiploid childhood acute lymphoblastic leukemia.
|
17910045 |
2008 |
|
rs121913529
|
|
G |
0.790 |
CausalMutation |
CLINVAR |
Frequency and distinctive spectrum of KRAS mutations in never smokers with lung adenocarcinoma.
|
18794081 |
2008 |
|
rs121913529
|
|
T |
0.790 |
CausalMutation |
CLINVAR |
Frequency and distinctive spectrum of KRAS mutations in never smokers with lung adenocarcinoma.
|
18794081 |
2008 |
|
rs121913529
|
|
T |
0.790 |
CausalMutation |
CLINVAR |
Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers.
|
19029981 |
2008 |
|
rs121913529
|
|
A |
0.790 |
CausalMutation |
CLINVAR |
Correlation of clinical features with the mutational status of GM-CSF signaling pathway-related genes in juvenile myelomonocytic leukemia.
|
19047918 |
2009 |
|
rs121913529
|
|
T |
0.790 |
CausalMutation |
CLINVAR |
Correlation of clinical features with the mutational status of GM-CSF signaling pathway-related genes in juvenile myelomonocytic leukemia.
|
19047918 |
2009 |
|
rs121913529
|
|
A |
0.790 |
CausalMutation |
CLINVAR |
KRAS mutation analysis in ovarian samples using a high sensitivity biochip assay.
|
19358724 |
2009 |
|
rs121913529
|
|
T |
0.790 |
CausalMutation |
CLINVAR |
KRAS mutation analysis in ovarian samples using a high sensitivity biochip assay.
|
19358724 |
2009 |
|
rs121913529
|
|
A |
0.790 |
GeneticVariation |
CLINVAR |
A synthetic lethal interaction between K-Ras oncogenes and Cdk4 unveils a therapeutic strategy for non-small cell lung carcinoma.
|
20609353 |
2010 |
|
rs121913529
|
|
A |
0.790 |
CausalMutation |
CLINVAR |
KRAS(G12V) enhances proliferation and initiates myelomonocytic differentiation in human stem/progenitor cells via intrinsic and extrinsic pathways.
|
21169357 |
2011 |
|
rs121913529
|
|
A |
0.790 |
GeneticVariation |
CLINVAR |
Effect of simvastatin on cetuximab resistance in human colorectal cancer with KRAS mutations.
|
21398618 |
2011 |
|
rs121913529
|
|
A |
0.790 |
GeneticVariation |
CLINVAR |
Mechanisms of resistance to crizotinib in patients with ALK gene rearranged non-small cell lung cancer.
|
22235099 |
2012 |
|
rs121913529
|
|
|
0.790 |
GeneticVariation |
BEFREE |
NSCLC cell lines with mutant KRas-Gly12Asp had activated phosphatidylinositol 3-kinase (PI-3-K) and mitogen-activated protein/extracellular signal-regulated kinase kinase (MEK) signaling, whereas those with mutant KRas-Gly12Cys or mutant KRas-Gly12Val had activated Ral signaling and decreased growth factor-dependent Akt activation.
|
22247021 |
2012 |
|
rs121913529
|
|
A |
0.790 |
GeneticVariation |
CLINVAR |
Therapeutic effect of γ-secretase inhibition in KrasG12V-driven non-small cell lung carcinoma by derepression of DUSP1 and inhibition of ERK.
|
22897852 |
2012 |
|
rs121913529
|
|
|
0.790 |
GeneticVariation |
BEFREE |
Using genetically engineered mouse models (GEMMs) for human non-small-cell lung cancer (NSCLC), we found that deletion of the essential autophagy gene, Atg7, in KRAS(G12D)-driven NSCLC inhibits tumor growth and converts adenomas and adenocarcinomas to benign oncocytomas characterized by the accumulation of respiration-defective mitochondria.
|
23959381 |
2013 |
|
rs121913529
|
|
A |
0.790 |
GeneticVariation |
CLINVAR |
Prospective enterprise-level molecular genotyping of a cohort of cancer patients.
|
25157968 |
2014 |