Gene: KRAS ×
Source: INFERRED ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs112445441
rs112445441
KRAS
G 0.700 CausalMutation CLINVAR Frequency and distinctive spectrum of KRAS mutations in never smokers with lung adenocarcinoma. 18794081

2008
dbSNP: rs112445441
rs112445441
KRAS
T 0.700 CausalMutation CLINVAR KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib. 15696205

2005
dbSNP: rs112445441
rs112445441
KRAS
G 0.700 CausalMutation CLINVAR BRAF and RAS mutations in human lung cancer and melanoma. 12460918

2002
dbSNP: rs112445441
rs112445441
KRAS
T 0.700 CausalMutation CLINVAR Frequency and distinctive spectrum of KRAS mutations in never smokers with lung adenocarcinoma. 18794081

2008
dbSNP: rs112445441
rs112445441
KRAS
T 0.700 CausalMutation CLINVAR BRAF and RAS mutations in human lung cancer and melanoma. 12460918

2002
dbSNP: rs121913238
rs121913238
KRAS
T 0.700 CausalMutation CLINVAR Frequency and distinctive spectrum of KRAS mutations in never smokers with lung adenocarcinoma. 18794081

2008
dbSNP: rs121913238
rs121913238
KRAS
T 0.700 CausalMutation CLINVAR Correlation of clinical features with the mutational status of GM-CSF signaling pathway-related genes in juvenile myelomonocytic leukemia. 19047918

2009
dbSNP: rs121913238
rs121913238
KRAS
T 0.700 CausalMutation CLINVAR BRAF and RAS mutations in human lung cancer and melanoma. 12460918

2002
dbSNP: rs121913240
rs121913240
KRAS
A 0.700 CausalMutation CLINVAR BRAF and RAS mutations in human lung cancer and melanoma. 12460918

2002
dbSNP: rs121913240
rs121913240
KRAS
C 0.700 CausalMutation CLINVAR BRAF and RAS mutations in human lung cancer and melanoma. 12460918

2002
dbSNP: rs121913240
rs121913240
KRAS
C 0.700 CausalMutation CLINVAR Frequency and distinctive spectrum of KRAS mutations in never smokers with lung adenocarcinoma. 18794081

2008
dbSNP: rs121913240
rs121913240
KRAS
A 0.700 CausalMutation CLINVAR KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib. 15696205

2005
dbSNP: rs121913240
rs121913240
KRAS
A 0.700 CausalMutation CLINVAR Erlotinib for frontline treatment of advanced non-small cell lung cancer: a phase II study. 17062680

2006
dbSNP: rs121913240
rs121913240
KRAS
A 0.700 CausalMutation CLINVAR Frequency and distinctive spectrum of KRAS mutations in never smokers with lung adenocarcinoma. 18794081

2008
dbSNP: rs121913529
rs121913529
KRAS
T 0.790 CausalMutation CLINVAR Spontaneous improvement of hematologic abnormalities in patients having juvenile myelomonocytic leukemia with specific RAS mutations. 17332249

2007
dbSNP: rs121913529
rs121913529
KRAS
T 0.790 CausalMutation CLINVAR Correlation of clinical features with the mutational status of GM-CSF signaling pathway-related genes in juvenile myelomonocytic leukemia. 19047918

2009
dbSNP: rs121913529
rs121913529
KRAS
A 0.790 GeneticVariation CLINVAR Mechanisms of resistance to crizotinib in patients with ALK gene rearranged non-small cell lung cancer. 22235099

2012
dbSNP: rs121913529
rs121913529
KRAS
A 0.790 CausalMutation CLINVAR KRAS mutation analysis in ovarian samples using a high sensitivity biochip assay. 19358724

2009
dbSNP: rs121913529
rs121913529
KRAS
A 0.790 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014
dbSNP: rs121913529
rs121913529
KRAS
A 0.790 CausalMutation CLINVAR Correlation of clinical features with the mutational status of GM-CSF signaling pathway-related genes in juvenile myelomonocytic leukemia. 19047918

2009
dbSNP: rs121913529
rs121913529
KRAS
A 0.790 CausalMutation CLINVAR KRAS(G12V) enhances proliferation and initiates myelomonocytic differentiation in human stem/progenitor cells via intrinsic and extrinsic pathways. 21169357

2011
dbSNP: rs121913529
rs121913529
KRAS
A 0.790 CausalMutation CLINVAR KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib. 15696205

2005
dbSNP: rs121913529
rs121913529
KRAS
G 0.790 CausalMutation CLINVAR KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib. 15696205

2005
dbSNP: rs121913529
rs121913529
KRAS
A 0.790 GeneticVariation CLINVAR Therapeutic effect of γ-secretase inhibition in KrasG12V-driven non-small cell lung carcinoma by derepression of DUSP1 and inhibition of ERK. 22897852

2012
dbSNP: rs121913529
rs121913529
KRAS
T 0.790 CausalMutation CLINVAR Mutations of FLT3, NRAS, KRAS, and PTPN11 are frequent and possibly mutually exclusive in high hyperdiploid childhood acute lymphoblastic leukemia. 17910045

2008