Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs17635492
rs17635492
0.800 GeneticVariation GWASCAT A genome-wide association study of survival in small-cell lung cancer patients treated with irinotecan plus cisplatin chemotherapy. 23478653

2014

dbSNP: rs17635492
rs17635492
0.800 GeneticVariation GWASDB A genome-wide association study of survival in small-cell lung cancer patients treated with irinotecan plus cisplatin chemotherapy. 23478653

2014

dbSNP: rs2018683
rs2018683
0.800 GeneticVariation GWASDB A genome-wide association study of survival in small-cell lung cancer patients treated with irinotecan plus cisplatin chemotherapy. 23478653

2014

dbSNP: rs2018683
rs2018683
T 0.800 GeneticVariation GWASCAT A genome-wide association study of survival in small-cell lung cancer patients treated with irinotecan plus cisplatin chemotherapy. 23478653

2014

dbSNP: rs344924
rs344924
0.800 GeneticVariation GWASDB A genome-wide association study of survival in small-cell lung cancer patients treated with irinotecan plus cisplatin chemotherapy. 23478653

2014

dbSNP: rs344924
rs344924
0.800 GeneticVariation GWASCAT A genome-wide association study of survival in small-cell lung cancer patients treated with irinotecan plus cisplatin chemotherapy. 23478653

2014

dbSNP: rs7186128
rs7186128
G 0.800 GeneticVariation GWASCAT A genome-wide association study of survival in small-cell lung cancer patients treated with irinotecan plus cisplatin chemotherapy. 23478653

2014

dbSNP: rs7186128
rs7186128
0.800 GeneticVariation GWASDB A genome-wide association study of survival in small-cell lung cancer patients treated with irinotecan plus cisplatin chemotherapy. 23478653

2014

dbSNP: rs10429489
rs10429489
A 0.700 GeneticVariation GWASCAT Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations. 31326317

2019

dbSNP: rs11674251
rs11674251
0.700 GeneticVariation GWASDB The 18p11.22 locus is associated with never smoker non-small cell lung cancer susceptibility in Korean populations. 21866343

2012

dbSNP: rs1209950
rs1209950
T 0.700 GeneticVariation GWASCAT Genome-wide association study on overall survival of advanced non-small cell lung cancer patients treated with carboplatin and paclitaxel. 21079520

2011

dbSNP: rs12296850
rs12296850
A 0.700 GeneticVariation GWASCAT Genome-wide association study identifies a novel susceptibility locus at 12q23.1 for lung squamous cell carcinoma in han chinese. 23341777

2013

dbSNP: rs1454694
rs1454694
C 0.700 GeneticVariation GWASCAT A genetic polymorphism rs1454694 was identified as a novel genetic risk factor for RFS of stage I NSCLCs. 24737549

2014

dbSNP: rs10503380
rs10503380
0.010 GeneticVariation BEFREE TNKS1 SNPs (rs11991621 rs10503380, and rs7015700) were associated with NSCLC risk, whereas rs6601328 and rs12541709 inversely associated with NSCLC or ADC risk in this Chinese population. 26617760

2015

dbSNP: rs10878232
rs10878232
0.010 GeneticVariation BEFREE Using online databases, we found rs10878232 displayed expression quantitative trait loci correlation with the expression of LEMD3, a neighboring gene previously associated with NSCLC survival. 24980784

2014

dbSNP: rs11646213
rs11646213
0.010 GeneticVariation BEFREE Our results indicated that the rs11646213 and rs7195409 in <i>CDH13</i> could be associated with NSCLC</span> or its pathologic stages in the Chinese Han population. 29416663

2018

dbSNP: rs11991621
rs11991621
0.010 GeneticVariation BEFREE TNKS1 SNPs (rs11991621 rs10503380, and rs7015700) were associated with NSCLC risk, whereas rs6601328 and rs12541709 inversely associated with NSCLC or ADC risk in this Chinese population. 26617760

2015

dbSNP: rs12000445
rs12000445
0.010 GeneticVariation BEFREE The minor allele of three SNPs (rs7629386 at 3p22.1, rs969088 at 5p14.1, and rs3850370 at 14q24.3) were associated with worse NSCLC survival while 2 (rs41997 at 7q31.31 and rs12000445 at 9p21.3) were associated with better NSCLC survival. 22872573

2012

dbSNP: rs12621220
rs12621220
0.010 GeneticVariation BEFREE For rs12621220G>A (-3893) and rs1143623G>C (-1464), heterozygous variants, when compared with ancestral genotype, were significantly associated with decreased risk of NSCLC, with adjusted odds ratio (aOR)=0.710 (0.516, 0.976), P=0.035 and aOR=0.643 (0.466, 0.886), P=0.007, respectively. 26141218

2015

dbSNP: rs12621220
rs12621220
0.010 GeneticVariation BEFREE IL1B rs12621220G/A (-3893), rs1143623G/C (-1464), rs16944T/C (-511) and rs1143627C/T (-31) were previously reported to be associated with non-small cell lung cancer (NSCLC) and formed a specific haplotype (GGCT) which was associated with increased IL1B gene expression and increased risk of NSCLC in European populations. 26141218

2015

dbSNP: rs1414493
rs1414493
0.010 GeneticVariation BEFREE Our results showed that SDHC gene: SNP rs12064957, IDH2 gene: SNP rs11540478 and FH gene: SNP rs1414493 were associated with overall survival (OS) and SDHA gene: SNP rs13173911, IDH2 gene: SNP rs4932158 were associated with recurrence-free survival (RFS) of NSCLC patients. 25576295

2015

dbSNP: rs1957860
rs1957860
0.010 GeneticVariation BEFREE We, therefore, performed a case-control study to investigate the association of seven selected single nucleotide polymorphisms (SNPs), in genes coding for excision repair cross-complimentary group 1 (ERCC1: rs11615, rs3212986, rs2298881), nuclear factor ĸB (NFKB2: rs7897947, rs12769316), bone morphogenetic protein 4 (BMP4: rs1957860), complement receptor 1 (CR1: rs7525160) and del/ins polymorphism in the family hypoxia inducible factor 2 gene (EGLN2: rs10680577), with non-small cell lung cancer (NSCLC) risk. 31177178

2019

dbSNP: rs2270628
rs2270628
0.010 GeneticVariation BEFREE With an aim to determine the association of variations in <i>IGF2BP2</i> and <i>IGFBP3</i> genes with risk of non-small-cell lung cancer (NSCLC), <i>IGF2BP2</i> rs1470579 A>C, rs4402960 G>T and <i>IGFBP3</i> rs2270628 C>T, rs3110697 G>A, and rs6953668 G>A polymorphisms were selected and genotyped in 521 NSCLC patients and 1,030 controls. 30214291

2018

dbSNP: rs4743325
rs4743325
0.010 GeneticVariation BEFREE A 2-tSNP AT haplotype reconstructed with tSNP rs7040869 and rs4743325, in linkage disequilibrium with each other, was strongly associated with NSCLC cases displaying ASE (P=0.01). 21225232

2011

dbSNP: rs6122390
rs6122390
0.010 GeneticVariation BEFREE Additionally, the combined analysis of these 5 SNPs showed a significant locus-dosage effect between number of unfavorable alleles (rs919968-A, rs3775815-C, rs4867902-G, rs6122390-A, and rs298206-T) and death risk of NSCLC (P for trend < 0.001). 26632718

2015