Gene: PIK3CA ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs121913273
rs121913273
PIK3CA
A 0.700 CausalMutation CLINVAR Breast tumor cells with PI3K mutation or HER2 amplification are selectively addicted to Akt signaling. 18725974

2008
dbSNP: rs121913273
rs121913273
PIK3CA
A 0.700 CausalMutation CLINVAR Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers. 19029981

2008
dbSNP: rs121913279
rs121913279
PIK3CA
G 0.700 CausalMutation CLINVAR Breast tumor cells with PI3K mutation or HER2 amplification are selectively addicted to Akt signaling. 18725974

2008
dbSNP: rs121913279
rs121913279
PIK3CA
G 0.700 CausalMutation CLINVAR Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers. 19029981

2008
dbSNP: rs121913279
rs121913279
PIK3CA
T 0.700 CausalMutation CLINVAR Breast tumor cells with PI3K mutation or HER2 amplification are selectively addicted to Akt signaling. 18725974

2008
dbSNP: rs121913279
rs121913279
PIK3CA
T 0.700 CausalMutation CLINVAR Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers. 19029981

2008
dbSNP: rs104886003
rs104886003
PIK3CA
C 0.700 CausalMutation CLINVAR PIK3CA mutation status in Japanese lung cancer patients. 16930767

2006
dbSNP: rs104886003
rs104886003
PIK3CA
C 0.700 CausalMutation CLINVAR Allelic dilution obscures detection of a biologically significant resistance mutation in EGFR-amplified lung cancer. 16906227

2006
dbSNP: rs104886003
rs104886003
PIK3CA
A 0.700 CausalMutation CLINVAR Allelic dilution obscures detection of a biologically significant resistance mutation in EGFR-amplified lung cancer. 16906227

2006
dbSNP: rs104886003
rs104886003
PIK3CA
A 0.700 CausalMutation CLINVAR PIK3CA mutation status in Japanese lung cancer patients. 16930767

2006
dbSNP: rs121913273
rs121913273
PIK3CA
A 0.700 CausalMutation CLINVAR PIK3CA mutation status in Japanese lung cancer patients. 16930767

2006
dbSNP: rs121913273
rs121913273
PIK3CA
A 0.700 CausalMutation CLINVAR Allelic dilution obscures detection of a biologically significant resistance mutation in EGFR-amplified lung cancer. 16906227

2006
dbSNP: rs121913279
rs121913279
PIK3CA
T 0.700 CausalMutation CLINVAR Allelic dilution obscures detection of a biologically significant resistance mutation in EGFR-amplified lung cancer. 16906227

2006
dbSNP: rs121913279
rs121913279
PIK3CA
T 0.700 CausalMutation CLINVAR PIK3CA mutation status in Japanese lung cancer patients. 16930767

2006
dbSNP: rs121913279
rs121913279
PIK3CA
G 0.700 CausalMutation CLINVAR Allelic dilution obscures detection of a biologically significant resistance mutation in EGFR-amplified lung cancer. 16906227

2006
dbSNP: rs121913279
rs121913279
PIK3CA
G 0.700 CausalMutation CLINVAR PIK3CA mutation status in Japanese lung cancer patients. 16930767

2006
dbSNP: rs104886003
rs104886003
PIK3CA
A 0.700 CausalMutation CLINVAR Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic. 15647370

2005
dbSNP: rs104886003
rs104886003
PIK3CA
C 0.700 CausalMutation CLINVAR Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic. 15647370

2005
dbSNP: rs121913273
rs121913273
PIK3CA
A 0.700 CausalMutation CLINVAR Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic. 15647370

2005
dbSNP: rs121913279
rs121913279
PIK3CA
T 0.700 CausalMutation CLINVAR Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic. 15647370

2005
dbSNP: rs121913279
rs121913279
PIK3CA
G 0.700 CausalMutation CLINVAR Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic. 15647370

2005
dbSNP: rs104886003
rs104886003
PIK3CA
C 0.700 CausalMutation CLINVAR High frequency of mutations of the PIK3CA gene in human cancers. 15016963

2004
dbSNP: rs104886003
rs104886003
PIK3CA
A 0.700 CausalMutation CLINVAR High frequency of mutations of the PIK3CA gene in human cancers. 15016963

2004
dbSNP: rs104886003
rs104886003
PIK3CA
C 0.700 CausalMutation CLINVAR The PIK3CA gene is mutated with high frequency in human breast cancers. 15254419

2004
dbSNP: rs104886003
rs104886003
PIK3CA
A 0.700 CausalMutation CLINVAR The PIK3CA gene is mutated with high frequency in human breast cancers. 15254419

2004