Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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C | 0.730 | GeneticVariation | GWASCAT | Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations. | 31326317 | 2019 |
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0.730 | GeneticVariation | BEFREE | Survival analysis showed no prognostic value for rs401681 polymorphisms or telomere length in NSCLC. | 29033187 | 2017 |
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0.730 | GeneticVariation | BEFREE | In the analysis of the association between rs401681 and non-small cell lung cancer (NSCLC) risks, all of the contrast models showed similar results except the CT vs. CC genetic model (OR = 0.93, 95 % CI = 0.84-1.02, P het = 0.568). | 24957041 | 2014 |
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0.730 | GeneticVariation | BEFREE | We found that the rs401681C/T allele in the TERT-CLPTM1L gene was associated with the risk of non-small cell lung cancer [NSCLC; P = 0.012, odds ratio (OR) = 1.29, 95% confidence interval (95%CI) = 1.09-1.50], but was not associated with the risk of small cell lung cancer (P = 0.571, OR = 1.15, 95%CI = 0.82-1.47). | 23359026 | 2013 |
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0.020 | GeneticVariation | BEFREE | The results from our replication study and the meta-analysis provided firm evidence that rs402710 T allele significantly contributed to decreased lung cancer risk, and the case-control study implied that the variant may yield stronger effect on NSCLC and never smokers. | 24194831 | 2013 |
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0.020 | GeneticVariation | BEFREE | However, no significant association was found between rs402710C/T and NSCLC risk. | 19369581 | 2009 |
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0.010 | GeneticVariation | BEFREE | We selected three single-nucleotide polymorphisms of TERT-CLPTM1L (rs2853669, rs2736108 and rs31490) and genotyped in 140 early stage NSCLC patients by TaqMan assay. | 27982019 | 2017 |