Gene: ERBB2 ×
Source: BEFREE ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs372043866
rs372043866
ERBB2
0.020 GeneticVariation BEFREE Here, we report a case of an advanced chemotherapy-resistant NSCLC, harboring a novel HER3(V855A) somatic mutation homologous to the EGFR(L858R)activating mutation. 26689995

2016
dbSNP: rs372043866
rs372043866
ERBB2
0.020 GeneticVariation BEFREE It is indicated for the first-line treatment of patients with metastatic non-small cell lung cancer (NSCLC) carrying EGFR exon 19 deletions or exon 21 (L858R) mutations. 24844234

2014
dbSNP: rs758222990
rs758222990
ERBB2 ; MIR4728
0.010 GeneticVariation BEFREE This is the first case report describing a NSCLC patient harboring a rare <i>HER2</i> R896G mutation who responds to afatinib. 31849493

2019