DisGeNET - a database of gene-disease associations

Renal Cell Carcinoma, C0007134

Variant: rs1222213359 ×

Source: BEFREE ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs1222213359

VEGFA

0.030

GeneticVariation

BEFREE

Moreover, VEGF -1154G/A and -634C/G polymorphisms were found significantly associated with poor OS of RCC.

28489583

2017

dbSNP:

rs1222213359

VEGFA

0.030

GeneticVariation

BEFREE

In conclusion, our study presented the factors regarding the prognosis of RCC patients, and high platelet and neutrophil counts, low lymphocytes, and VEGF -2578C/A and -1154G/A polymorphisms were shown to be independent factors for a lower prognosis of RCC patients.

25062489

2014

dbSNP:

rs1222213359

VEGFA

0.030

GeneticVariation

BEFREE

We investigated the associations of three polymorphisms (-2578C/A, -1154G/A, and -634C/G) in the VEGF gene with the clinicopathologic parameters and survival of 213 patients with RCC.

17287073

2007