Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs754332870
rs754332870
0.010 GeneticVariation BEFREE Analysis of the KRAS gene showed only a G12C variation in one large cell carcinoma (LCC) patient, whereas variants were not found in adenocarcinoma (ADC) and squamous cell carcinoma (SCC) cases. 30048458

2018

dbSNP: rs762846821
rs762846821
0.010 GeneticVariation BEFREE We also studied genetically induced SCCs that expressed G12D mutant Kras (Kras G12D) but were deficient for p53. 26168291

2015

dbSNP: rs587783064
rs587783064
0.010 GeneticVariation BEFREE Therefore, the FGFR4 Gly388Arg polymorphism and TP53 mutations, as well as their combinations, are excellent predictors of the prognosis for OSCC patients. 20127014

2010

dbSNP: rs1057520001
rs1057520001
0.010 GeneticVariation BEFREE The results for the p21 Ser31Arg polymorphism suggested that 31Ser is a moderate-risk allele for squamous-cell carcinoma. 17059853

2007

dbSNP: rs886039484
rs886039484
0.010 GeneticVariation BEFREE The results for the p21 Ser31Arg polymorphism suggested that 31Ser is a moderate-risk allele for squamous-cell carcinoma. 17059853

2007

dbSNP: rs587782289
rs587782289
0.010 GeneticVariation BEFREE An SNP, Thr706Ala, in the POLI gene encoding another translesion DNA polymerase was associated with adenocarcinoma and squamous cell carcinoma risk, particularly in individuals of ages < 61 years (OR Ala/Ala + Ala/Thr vs. Thr/Thr = 1.5 and 2.4, respectively). 15609317

2005

dbSNP: rs1057520004
rs1057520004
0.010 GeneticVariation BEFREE The 12th mutation GTG-->GGG (valine-->glycine) at codon 216 was expressed in line SCC-12 clone B along with an apparently normal p53 allele and is to our knowledge a novel mutation. 8390283

1993

dbSNP: rs1131691014
rs1131691014
0.080 GeneticVariation BEFREE In this study, we analyzed the association of TP53 Pro72Arg polymorphism with squamous cell carcinoma of oral tongue (SCCOT) and esophagus (ESCC) in India. 25436609

2014

dbSNP: rs878854066
rs878854066
0.080 GeneticVariation BEFREE In this study, we analyzed the association of TP53 Pro72Arg polymorphism with squamous cell carcinoma of oral tongue (SCCOT) and esophagus (ESCC) in India. 25436609

2014

dbSNP: rs1131691014
rs1131691014
0.080 GeneticVariation BEFREE Polymorphism Arg72Pro of p53 confers susceptibility to squamous cell carcinoma of lungs in a North Indian population. 23317414

2013

dbSNP: rs1131691014
rs1131691014
0.080 GeneticVariation BEFREE P53 (Pro72Arg) polymorphism associated with the risk of oral squamous cell carcinoma in gutka, niswar and manpuri addicted patients of Pakistan. 23683469

2013

dbSNP: rs878854066
rs878854066
0.080 GeneticVariation BEFREE Polymorphism Arg72Pro of p53 confers susceptibility to squamous cell carcinoma of lungs in a North Indian population. 23317414

2013

dbSNP: rs878854066
rs878854066
0.080 GeneticVariation BEFREE P53 (Pro72Arg) polymorphism associated with the risk of oral squamous cell carcinoma in gutka, niswar and manpuri addicted patients of Pakistan. 23683469

2013

dbSNP: rs1131691014
rs1131691014
0.080 GeneticVariation BEFREE We evaluated the effect of MDM2 SNP309 and its interaction with the p53 Arg72Pro polymorphism on pigmentary phenotypes and skin cancer risk in a nested case-control study within the Nurses' Health Study (NHS) among 219 melanoma cases, 286 squamous cell carcinoma (SCC) cases, 300 basal cell carcinoma (BCC) cases, and 873 controls, and among controls from other studies. 18814047

2009

dbSNP: rs1131691014
rs1131691014
0.080 GeneticVariation BEFREE In a large prospective cohort, p53 Arg72Pro Pro/Pro was associated with a 2-fold increased risk of death in all esophageal cancers, whereas MDM2 T309G G/G was associated with a 7-fold increased risk of death in squamous cell carcinoma. 19383811

2009

dbSNP: rs878854066
rs878854066
0.080 GeneticVariation BEFREE We evaluated the effect of MDM2 SNP309 and its interaction with the p53 Arg72Pro polymorphism on pigmentary phenotypes and skin cancer risk in a nested case-control study within the Nurses' Health Study (NHS) among 219 melanoma cases, 286 squamous cell carcinoma (SCC) cases, 300 basal cell carcinoma (BCC) cases, and 873 controls, and among controls from other studies. 18814047

2009

dbSNP: rs878854066
rs878854066
0.080 GeneticVariation BEFREE In a large prospective cohort, p53 Arg72Pro Pro/Pro was associated with a 2-fold increased risk of death in all esophageal cancers, whereas MDM2 T309G G/G was associated with a 7-fold increased risk of death in squamous cell carcinoma. 19383811

2009

dbSNP: rs1131691014
rs1131691014
0.080 GeneticVariation BEFREE Our data indicate that the TP53 Arg72Pro polymorphism increases the risk for squamous-cell carcinoma mainly in heavy smokers. 17059853

2007

dbSNP: rs878854066
rs878854066
0.080 GeneticVariation BEFREE Our data indicate that the TP53 Arg72Pro polymorphism increases the risk for squamous-cell carcinoma mainly in heavy smokers. 17059853

2007

dbSNP: rs1131691014
rs1131691014
0.080 GeneticVariation BEFREE We evaluated the association of the Arg72Pro polymorphism with skin cancer risk among Caucasians in a nested case-control study within the Nurses' Health Study (NHS) (219 melanoma, 286 squamous cell carcinoma (SCC), and 300 basal cell carcinoma (BCC) and 874 controls). 16739124

2006

dbSNP: rs878854066
rs878854066
0.080 GeneticVariation BEFREE We evaluated the association of the Arg72Pro polymorphism with skin cancer risk among Caucasians in a nested case-control study within the Nurses' Health Study (NHS) (219 melanoma, 286 squamous cell carcinoma (SCC), and 300 basal cell carcinoma (BCC) and 874 controls). 16739124

2006

dbSNP: rs1131691014
rs1131691014
0.080 GeneticVariation BEFREE p53 codon 72 ARG/PRO polymorphism is not related to HPV type or lesion grade in low- and high-grade squamous intra-epithelial lesions and invasive squamous carcinoma of the cervix. 10449610

1999

dbSNP: rs878854066
rs878854066
0.080 GeneticVariation BEFREE p53 codon 72 ARG/PRO polymorphism is not related to HPV type or lesion grade in low- and high-grade squamous intra-epithelial lesions and invasive squamous carcinoma of the cervix. 10449610

1999

dbSNP: rs1042522
rs1042522
0.090 GeneticVariation BEFREE Effect of TP53 rs1042522 on the susceptibility of patients to oral squamous cell carcinoma and oral leukoplakia: a meta-analysis. 30126398

2018

dbSNP: rs1042522
rs1042522
0.090 GeneticVariation BEFREE In this study, we analyzed the association of TP53 Pro72Arg polymorphism with squamous cell carcinoma of oral tongue (SCCOT) and esophagus (ESCC) in India. 25436609

2014