DisGeNET - a database of gene-disease associations

Squamous cell carcinoma, C0007137

Variant: rs1799782 ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs1799782

XRCC1

0.020

GeneticVariation

BEFREE

The Arg194Trp polymorphisms interacted with squamous cell carcinoma and affected overall survival of advanced NSCLC.

28081275

2016

dbSNP:

rs1799782

XRCC1

0.020

GeneticVariation

BEFREE

We found a significantly increased risk for basal cell carcinoma, squamous cell carcinoma and extramammary Paget's disease associated with Arg194Trp [adjusted odds ratio (AOR) = 2.347, 3.587, 3.741, 95 % confidence interval (CI) 1.02-5.39, 1.19-10.8, 1.15-12.2, respectively].

22639094

2012