Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs10927875
rs10927875
ZBTB17
0.800 GeneticVariation GWASCAT A genome-wide association study identifies two loci associated with heart failure due to dilated cardiomyopathy. 21459883

2011
dbSNP: rs10927875
rs10927875
ZBTB17
0.800 GeneticVariation GWASDB A genome-wide association study identifies two loci associated with heart failure due to dilated cardiomyopathy. 21459883

2011
dbSNP: rs2234962
rs2234962
BAG3
0.800 GeneticVariation GWASCAT A genome-wide association study identifies two loci associated with heart failure due to dilated cardiomyopathy. 21459883

2011
dbSNP: rs2234962
rs2234962
BAG3
0.800 GeneticVariation GWASDB A genome-wide association study identifies two loci associated with heart failure due to dilated cardiomyopathy. 21459883

2011
dbSNP: rs74315379
rs74315379
TNNT2
0.720 GeneticVariation BEFREE Gene-Targeted Mice with the Human Troponin T R141W Mutation Develop Dilated Cardiomyopathy with Calcium Desensitization. 27936050

2016
dbSNP: rs74315380
rs74315380
TNNT2
0.720 GeneticVariation BEFREE Gene-Targeted Mice with the Human Troponin T R141W Mutation Develop Dilated Cardiomyopathy with Calcium Desensitization. 27936050

2016
dbSNP: rs74315379
rs74315379
TNNT2
A 0.720 CausalMutation CLINVAR Effects of troponin T cardiomyopathy mutations on the calcium sensitivity of the regulated thin filament and the actomyosin cross-bridge kinetics of human β-cardiac myosin. 24367593

2013
dbSNP: rs74315379
rs74315379
TNNT2
A 0.720 CausalMutation CLINVAR Familial dilated cardiomyopathy mutations uncouple troponin I phosphorylation from changes in myofibrillar Ca²⁺ sensitivity. 23539503

2013
dbSNP: rs74315379
rs74315379
TNNT2
A 0.720 CausalMutation CLINVAR Disease-related cardiac troponins alter thin filament Ca2+ association and dissociation rates. 22675533

2012
dbSNP: rs74315380
rs74315380
TNNT2
A 0.720 GeneticVariation CLINVAR Disease-related cardiac troponins alter thin filament Ca2+ association and dissociation rates. 22675533

2012
dbSNP: rs74315380
rs74315380
TNNT2
A 0.720 GeneticVariation CLINVAR Sarcomere gene mutations in isolated left ventricular noncompaction cardiomyopathy do not predict clinical phenotype. 21551322

2011
dbSNP: rs59270054
rs59270054
LMNA
A 0.720 CausalMutation CLINVAR LMNA E82K mutation activates FAS and mitochondrial pathways of apoptosis in heart tissue specific transgenic mice. 21151901

2010
dbSNP: rs59270054
rs59270054
LMNA
A 0.720 CausalMutation CLINVAR Connexin 43 remodeling induced by LMNA gene mutation Glu82Lys in familial dilated cardiomyopathy with atrial ventricular block. 20497714

2010
dbSNP: rs59270054
rs59270054
LMNA
0.720 GeneticVariation BEFREE Heart tissue specific transgenic mice of human LMNA E82K, a mutation causing dilated cardiomyopathy, were generated. 21151901

2010
dbSNP: rs59270054
rs59270054
LMNA
A 0.720 CausalMutation CLINVAR Identification of a new lamin A/C mutation in a Chinese family affected with atrioventricular block as the prominent phenotype. 20155465

2010
dbSNP: rs74315379
rs74315379
TNNT2
A 0.720 CausalMutation CLINVAR Mutations in sarcomere protein genes in left ventricular noncompaction. 18506004

2008
dbSNP: rs74315379
rs74315379
TNNT2
A 0.720 CausalMutation CLINVAR [Association of TNNT2 gene mutations with idiopathic dilated cardiomyopathy in a Chengdu population]. 19253838

2008
dbSNP: rs74315380
rs74315380
TNNT2
A 0.720 GeneticVariation CLINVAR Mutations in sarcomere protein genes in left ventricular noncompaction. 18506004

2008
dbSNP: rs59270054
rs59270054
LMNA
A 0.720 CausalMutation CLINVAR [Effects of a novel familial dilated cardiomyopathy associated LMNA gene mutation E82K on cell cycle of HEK293 cells]. 17386158

2007
dbSNP: rs74315379
rs74315379
TNNT2
A 0.720 CausalMutation CLINVAR Dilated and hypertrophic cardiomyopathy mutations in troponin and alpha-tropomyosin have opposing effects on the calcium affinity of cardiac thin filaments. 17932326

2007
dbSNP: rs74315380
rs74315380
TNNT2
A 0.720 GeneticVariation CLINVAR Dilated and hypertrophic cardiomyopathy mutations in troponin and alpha-tropomyosin have opposing effects on the calcium affinity of cardiac thin filaments. 17932326

2007
dbSNP: rs59270054
rs59270054
LMNA
A 0.720 CausalMutation CLINVAR Mutation Glu82Lys in lamin A/C gene is associated with cardiomyopathy and conduction defect. 16630578

2006
dbSNP: rs59270054
rs59270054
LMNA
0.720 GeneticVariation BEFREE We screened genetic mutations in a large Chinese family of 50 members including members with dilated cardiomyopathy and found a Glu82Lys substitution mutation in the rod domain of the lamin A/C protein in eight family members, three of them have been diagnosed as dilated cardiomyopathy, one presented with heart dilation. 16630578

2006
dbSNP: rs59270054
rs59270054
LMNA
A 0.720 CausalMutation CLINVAR [A novel LMNA gene mutation E82K associated with familial dilated cardiomyopathy]. 16266469

2005
dbSNP: rs74315379
rs74315379
TNNT2
A 0.720 CausalMutation CLINVAR Mutation screening in dilated cardiomyopathy: prominent role of the beta myosin heavy chain gene. 15769782

2005