|
rs1126616
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found an association between rs1126616 and global CP (corrected allelic P = 0.0006 and genotypic P = 0.0011 after Bonferroni correction).
|
27114095 |
2016 |
|
rs11728697
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To explore the genetic association between OPN gene single nucleotide polymorphisms (SNPs) and CP in the Chinese Han population, five SNPs (rs2853744, rs2853749, rs11728697, rs4754, and rs1126616) were genotyped among 715 CP patients and 658 healthy controls using the MassArray platform.
|
27114095 |
2016 |
|
rs1411040
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Significant association was found for an association between CP and rs1961495 (allele: p = 0.008, odds ratio (OR) = 1.387, 95% confidence interval (CI) = 1.088-1.767) and rs1411040 (allele: p = 0.009, OR = 1.746, 95% CI = 1.148-2.656) SNPs of the COL4A1 gene.
|
26748532 |
2016 |
|
rs1799724
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Also, a significant increase in the risk of CP was observed to be associated with the interactions of TNF-α rs1799724 and MTHFR rs9651118 (OR 2.75, 95 % CI 1.23-6.13).
|
26646537 |
2016 |
|
rs1961495
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Significant association was found for an association between CP and rs1961495 (allele: p = 0.008, odds ratio (OR) = 1.387, 95% confidence interval (CI) = 1.088-1.767) and rs1411040 (allele: p = 0.009, OR = 1.746, 95% CI = 1.148-2.656) SNPs of the COL4A1 gene.
|
26748532 |
2016 |
|
rs2853744
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To explore the genetic association between OPN gene single nucleotide polymorphisms (SNPs) and CP in the Chinese Han population, five SNPs (rs2853744, rs2853749, rs11728697, rs4754, and rs1126616) were genotyped among 715 CP patients and 658 healthy controls using the MassArray platform.
|
27114095 |
2016 |
|
rs2853749
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To explore the genetic association between OPN gene single nucleotide polymorphisms (SNPs) and CP in the Chinese Han population, five SNPs (rs2853744, rs2853749, rs11728697, rs4754, and rs1126616) were genotyped among 715 CP patients and 658 healthy controls using the MassArray platform.
|
27114095 |
2016 |
|
rs361525
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Subgroup analysis based on gestational age indicated a significant association between rs361525 and rs9651118 and CP with or without premature.
|
26646537 |
2016 |
|
rs4754
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To explore the genetic association between OPN gene single nucleotide polymorphisms (SNPs) and CP in the Chinese Han population, five SNPs (rs2853744, rs2853749, rs11728697, rs4754, and rs1126616) were genotyped among 715 CP patients and 658 healthy controls using the MassArray platform.
|
27114095 |
2016 |
|
rs9651118
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Also, a significant increase in the risk of CP was observed to be associated with the interactions of TNF-α rs1799724 and MTHFR rs9651118 (OR 2.75, 95 % CI 1.23-6.13).
|
26646537 |
2016 |
|
rs2735835
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the original population, SNP rs2735835 was associated with CP; the minor allele A was underrepresented in cases compared to controls (OR = 0.42, 95% CI: 0.21-0.83, p = 0.01).
|
26113374 |
2015 |
|
rs59007384
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Children with CP were more likely than expected to carry the APOEε3 allele (RR 7.5; CI: 0.99-53.7 for heterozygotes and 10.3; CI: 1.4-79.6 for homozygotes), and to have the haplotype of APOEε3 and rs59007384 G (RR 2.4; CI: 1-5.7 for heterozygotes, RR 3.7; CI: 1.4-9.5 for homozygotes) whereas the distribution was as expected for rs59007384 alone.
|
25596901 |
2015 |
|
rs121918399
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A haplotype consisting of the five SNPs rs769446(C), rs405509(C), rs121918399(C), rs429358(T), and rs190853081(G) was associated with a decreased risk of CP (P = 0.002 after Bonferroni correction).
|
24522486 |
2014 |
|
rs1800796
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Differences were found between spastic CP and controls in males for rs2069837; between CP with periventricular leukomalacia and controls in males for rs1800796 and rs2066992; and between term CP and controls in males for rs2069837.
|
24903966 |
2014 |
|
rs190853081
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A haplotype consisting of the five SNPs rs769446(C), rs405509(C), rs121918399(C), rs429358(T), and rs190853081(G) was associated with a decreased risk of CP (P = 0.002 after Bonferroni correction).
|
24522486 |
2014 |
|
rs2066992
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Differences were found between spastic CP and controls in males for rs2069837; between CP with periventricular leukomalacia and controls in males for rs1800796 and rs2066992; and between term CP and controls in males for rs2069837.
|
24903966 |
2014 |
|
rs2069837
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Differences were found between spastic CP and controls in males for rs2069837; between CP with periventricular leukomalacia and controls in males for rs1800796 and rs2066992; and between term CP and controls in males for rs2069837.
|
24903966 |
2014 |
|
rs405509
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A haplotype consisting of the five SNPs rs769446(C), rs405509(C), rs121918399(C), rs429358(T), and rs190853081(G) was associated with a decreased risk of CP (P = 0.002 after Bonferroni correction).
|
24522486 |
2014 |
|
rs429358
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No significant association was detected between the e4 identified by the C allele of rs429</span>358 and CP, but there were significant differences in allelic frequencies between the CP patients and controls at rs769446 (P = 0.005, P = 0.025 after Bonferroni correction), as well as between the CP patients with preterm birth (<34 gestational weeks) and controls at rs769446 (P = 0.001, P = 0.005 after Bonferroni correction).
|
24522486 |
2014 |
|
rs769446
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No significant association was detected between the e4 identified by the C allele of rs429358 and CP, but there were significant differences in allelic frequencies between the CP patients and controls at rs769446 (P = 0.005, P = 0.025 after Bonferroni correction), as well as between the CP patients with preterm birth (<34 gestational weeks) and controls at rs769446 (P = 0.001, P = 0.005 after Bonferroni correction).
|
24522486 |
2014 |
|
rs1217401
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Subgroup analysis showed that rs1217401 of AP4B1 was significantly associated with CP as a sequela of hypoxic-ischemic encephalopathy (HIE) (CP + HIE) (allele: p = 0.042151; genotype: p = 4.46 × 10(-6)).
|
24065543 |
2013 |
|
rs1801131
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Subgroup analysis found statistically significant difference in allele and genotype frequencies between cases with both CP and MR (CP + MR) compared with both CP-only cases and controls at rs4846049, rs1476413 and rs1801131.
|
20962791 |
2011 |
|
rs4846049
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Subgroup analysis found statistically significant difference in allele and genotype frequencies between cases with both CP and MR (CP + MR) compared with both CP-only cases and controls at rs4846049, rs1476413 and rs1801131.
|
20962791 |
2011 |
|
rs1191926239
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study investigates associations between selected inflammatory mediator and cytokine gene polymorphisms (Toll-like receptor-4 (TLR-4) Asp299Gly, interleukin-6 G-174C and interleukin-4 C-589T) and CP from 443 CP infants and 883 control infants.
|
19566553 |
2009 |
|
rs4986790
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study investigates associations between selected inflammatory mediator and cytokine gene polymorphisms (Toll-like receptor-4 (TLR-4) Asp299Gly, interleukin-6 G-174C and interleukin-4 C-589T) and CP from 443 CP infants and 883 control infants.
|
19566553 |
2009 |