Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs231725
rs231725 		0.070 GeneticVariation BEFREE This study indicated that the polymorphisms of rs231775 and rs231725 would be the risk factors of PBC. 28642883

2017
dbSNP: rs231725
rs231725 		0.070 GeneticVariation BEFREE G allele of rs231775 and A allele of rs231725 were significantly associated with the risk of PBC. 23432218

2013
dbSNP: rs231725
rs231725 		0.070 GeneticVariation BEFREE The G allele of rs231775 is a risk factor for PBC, while AA genotype of rs3087243 and GG, GA and G allele of rs231725 show negative associations with PBC. 22414241

2012
dbSNP: rs231725
rs231725 		0.070 GeneticVariation BEFREE The CTLA-4 haplotype 1 (rs231775 G, rs231777 C, rs3087243 G, rs231725 A; GCGA) was a risk factor for PBC susceptibility but a protective factor for PBC progression. 21594562

2011
dbSNP: rs231725
rs231725 		0.070 GeneticVariation BEFREE TNF2A amplifies the CTLA4 rs231725 "A/A" genotype risk for PBC. 20578265

2010
dbSNP: rs231725
rs231725 		0.070 GeneticVariation BEFREE One CTLA4 gene SNP (rs231725) was significantly associated with susceptibility to anti-mitochondrial antibody (AMA)-positive PBC, but clinical significance disappeared after correction for multiple testing. 20557968

2010
dbSNP: rs231725
rs231725 		0.070 GeneticVariation BEFREE We identified a novel and relatively strong association between PBC and rs231725, a SNP in the 3' flanking region of CTLA4 located outside of the area previously investigated in PBC. 18778710

2008