rs887829
|
|
|
0.810 |
GeneticVariation |
BEFREE |
Indeed, this is the first report that interested in the study of polymorphisms in genes encoded for enzymes involved in the bilirubin metabolism: rs 4149056 of SLCO1B1 and rs4149000 of SLCO1A2 in combination with rs8175347 and rs887829 of UGT1A1 in order to find a correlation between the polymorphisms studied and the presence of gallstones in a population of sickle cell anemia (SCA) pediatric Tunisians.
|
26146896 |
2016 |
rs6742078
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The UGT1A1 Gilbert syndrome variant rs6742078 is associated with gallstone disease in men; further studies are required regarding the sex-specific physiology of bilirubin and bile acid metabolism.
|
20837016 |
2010 |
rs6742078
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Second, taking advantage of mendelian randomization, we tested whether a genetic variant in the bilirubin glucoronidating enzyme UGT1A1 (rs6742078) was associated with increased plasma bilirubin levels and, in turn, with an increased risk of symptomatic gallstone disease.
|
23753274 |
2013 |
rs8175347
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Indeed, this is the first report that interested in the study of polymorphisms in genes encoded for enzymes involved in the bilirubin metabolism: rs 4149056 of SLCO1B1 and rs4149000 of SLCO1A2 in combination with rs8175347 and rs887829 of UGT1A1 in order to find a correlation between the polymorphisms studied and the presence of gallstones in a population of sickle cell anemia (SCA) pediatric Tunisians.
|
26146896 |
2016 |
rs8175347
|
|
|
0.020 |
GeneticVariation |
BEFREE |
(TA) n repeat sequence (rs8175347) of UGT1A1 gene promoter polymorphism is associated with serum bilirubin levels and gallstones among different sickle cell anaemia (SCA) populations.
|
31619193 |
2019 |
rs4148323
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study shows that the combined TATA-box variants and G71R mutations of the UGT1A1 is associated with cholelithiasis in beta-thal/Hb E.
|
18081723 |
2008 |
rs887829
|
|
A |
0.810 |
GeneticVariation |
GWASCAT |
A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia.
|
22558097 |
2012 |
rs887829
|
|
A |
0.810 |
GeneticVariation |
GWASDB |
A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia.
|
22558097 |
2012 |