Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2235371
rs2235371
0.730 GeneticVariation BEFREE The genotype and allele frequencies of single nucleotide polymorphism rs2235371 in IRF6 showed significant differences in patients with cleft palate when compared to the controls, whereas no association was shown between rs642961, rs2236907, rs861019, and rs1044516 and non-syndromic orofacial clefts. 31495697

2019

dbSNP: rs2235371
rs2235371
C 0.730 GeneticVariation GWASCAT Genome-wide association study identifies a new susceptibility locus for cleft lip with or without a cleft palate. 25775280

2015

dbSNP: rs2235371
rs2235371
0.730 GeneticVariation BEFREE In the single locus analyses, we found rs642961 AG and AG/AA genotypes were associated with increased risk of NSOC, especially cleft lip with or without cleft palate (CL/P) and cleft lip with cleft palate (CLP), while significantly decreased risks were associated with rs2235371 CT and CT/TT genotypes. 20799332

2010

dbSNP: rs2235371
rs2235371
0.730 GeneticVariation BEFREE Association analysis between the IRF6 G820A polymorphism and nonsyndromic cleft lip and/or cleft palate in a Chinese population. 19115793

2009

dbSNP: rs2235375
rs2235375
0.010 GeneticVariation BEFREE IRF6 rs2235375 single nucleotide polymorphism is associated with isolated non-syndromic cleft palate but not with cleft lip with or without palate in South Indian population. 28712851

2018

dbSNP: rs2013162
rs2013162
0.010 GeneticVariation BEFREE Association of single-nucleotide polymorphisms, rs2235371 and rs2013162, in the IRF6 gene with non-syndromic cleft palate in northeast China. 27706679

2016