|
rs2632159
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<b>Conclusion:</b><i>PCAT1</i> rs2632159 SNP could be a biomarker for CRC risk.
|
31253700 |
2019 |
|
rs6983267
|
|
|
0.900 |
GeneticVariation |
BEFREE |
<i>CCAT2</i> rs6983267 was associated with the risk of CRC per</span> se (<i>p</i> < 0.01).
|
30841568 |
2019 |
|
rs6983267
|
|
|
0.900 |
GeneticVariation |
BEFREE |
A dose-dependent association was observed between CRC risk and genetic risk score, which is the aggregate number of alleles in six selected variants: 8q24 - rs6983267, 15q13 - rs4779584 and rs1696961, 14q22 - rs444435, 16q22 - rs9929218, and 3q26.2 - rs1093599.
|
26637073 |
2016 |
|
rs10505477
|
|
|
0.890 |
GeneticVariation |
GWASDB |
A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21.
|
17618284 |
2007 |
|
rs6983267
|
|
|
0.900 |
GeneticVariation |
GWASDB |
A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3.
|
18372905 |
2008 |
|
rs6983267
|
|
|
0.900 |
GeneticVariation |
GWASCAT |
A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3.
|
18372905 |
2008 |
|
rs6983267
|
|
|
0.900 |
GeneticVariation |
BEFREE |
A lower risk of CRC was associated with regular aspirin use and the T allele of rs6983267.
|
24317174 |
2013 |
|
rs10505477
|
|
|
0.890 |
GeneticVariation |
BEFREE |
A meta-analysis of included studies of rs10505477 polymorphisms identified allelic and genotypic associations with CRC risk in the US patients.
|
21722176 |
2011 |
|
rs7014346
|
|
A |
0.830 |
GeneticVariation |
GWASCAT |
A new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer.
|
25990418 |
2015 |
|
rs10505477
|
|
|
0.890 |
GeneticVariation |
BEFREE |
Among 1,861 incident cases and 1,937 population-based controls matched on age, gender, ethnicity, and clinic, rs10505477 was associated with risk of CRC in a dominant model, with an odds ratio = 1.23, 95% confidence interval = 1.05-1.43, (p = 0.008).
|
17630503 |
2007 |
|
rs6983267
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Among African Americans, the SNP rs6983267 at 8q24.21 was not associated with CRC (odds ratio, 1.18; P = .12); instead, the 8q24.21 SNP rs7014346 (odds ratio, 1.15; P = .03) was associated with CRC in this population.
|
20659471 |
2010 |
|
rs7014346
|
|
|
0.830 |
GeneticVariation |
BEFREE |
Among African Americans, the SNP rs6983267 at 8q24.21 was not associated with CRC (odds ratio, 1.18; P = .12); instead, the 8q24.21 SNP rs7014346 (odds ratio, 1.15; P = .03) was associated with CRC in this population.
|
20659471 |
2010 |
|
rs6983267
|
|
|
0.900 |
GeneticVariation |
BEFREE |
As expected, a significant association between the G allele of rs6983267 and CRC [OR, 1.22; 95% confidence interval (CI), 1.08-1.38; P = 0.0018] was found, confirming the previous observations.
|
18172290 |
2008 |
|
rs6983267
|
|
G |
0.900 |
GeneticVariation |
GWASCAT |
Association analyses identify 31 new risk loci for colorectal cancer susceptibility.
|
31089142 |
2019 |
|
rs6983267
|
|
G |
0.900 |
GeneticVariation |
GWASCAT |
Discovery of common and rare genetic risk variants for colorectal cancer.
|
30510241 |
2019 |
|
rs7013278
|
|
T |
0.710 |
GeneticVariation |
GWASCAT |
Discovery of common and rare genetic risk variants for colorectal cancer.
|
30510241 |
2019 |
|
rs6983267
|
|
T |
0.900 |
GeneticVariation |
GWASCAT |
Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies.
|
30104761 |
2018 |
|
rs7014346
|
|
|
0.830 |
GeneticVariation |
BEFREE |
Furthermore, the A allele of rs7014346, the A allele of rs10505477, and the T allele of rs4939827 were significantly related with an elevated risk of CRC only among Caucasian.Our study suggested that for CASC8 gene, SNP of rs7837328 and rs6983267 are risk factors for CRC among both Caucasian and Asian whereas rs7014346 and rs10505477 are risky gene polymorphisms only among Caucasian.
|
26579801 |
2015 |
|
rs10505477
|
|
|
0.890 |
GeneticVariation |
BEFREE |
Furthermore, the A allele of rs7014346, the A allele of rs10505477, and the T allele of rs4939827 were significantly related with an elevated risk of CRC only among Caucasian.Our study suggested that for CASC8 gene, SNP of rs7837328 and rs6983267 are risk factors for CRC among both Caucasian and Asian whereas rs7014346 and rs10505477 are risky gene polymorphisms only among Caucasian.
|
26579801 |
2015 |
|
rs7837328
|
|
|
0.720 |
GeneticVariation |
BEFREE |
Furthermore, the A allele of rs7014346, the A allele of rs10505477, and the T allele of rs4939827 were significantly related with an elevated risk of CRC only among Caucasian.Our study suggested that for CASC8 gene, SNP of rs7837328 and rs6983267 are risk factors for CRC among both Caucasian and Asian whereas rs7014346 and rs10505477 are risky gene polymorphisms only among Caucasian.
|
26579801 |
2015 |
|
rs6983267
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Furthermore, the A allele of rs7014346, the A allele of rs10505477, and the T allele of rs4939827 were significantly related with an elevated risk of CRC only among Caucasian.Our study suggested that for CASC8 gene, SNP of rs7837328 and rs6983267 are risk factors for CRC among both Caucasian and Asian whereas rs7014346 and rs10505477 are risky gene polymorphisms only among Caucasian.
|
26579801 |
2015 |
|
rs6983267
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Furthermore, the minor alleles of rs6983267 and rs1957636 were associated with worse CRC-specific and overall survival.
|
28567967 |
2017 |
|
rs7014346
|
|
A |
0.830 |
GeneticVariation |
GWASCAT |
Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21.
|
18372901 |
2008 |
|
rs7014346
|
|
A |
0.830 |
GeneticVariation |
GWASDB |
Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21.
|
18372901 |
2008 |
|
rs10505477
|
|
A |
0.890 |
GeneticVariation |
GWASCAT |
Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24.
|
17618283 |
2007 |