Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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A | 0.820 | GeneticVariation | GWASCAT | Large-Scale Genome-Wide Association Study of East Asians Identifies Loci Associated With Risk for Colorectal Cancer. | 30529582 | 2019 |
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A | 0.820 | GeneticVariation | GWASCAT | GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12. | 29471430 | 2018 |
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0.820 | GeneticVariation | BEFREE | Cumulative epidemiological evidence of an association was graded as strong for rs7903146 [odds ratio (OR) = 1.05, p = 4.13 × 10<sup>-5</sup> ] and rs7904519 (OR = 1.07, p = 2.02 × 10<sup>-14</sup> ) in breast cancer, rs11196172 (OR = 1.11, p = 2.22 × 10<sup>-16</sup> ), rs12241008 (OR = 1.13, p = 1.36 × 10<sup>-10</sup> ) and rs10506868 (OR = 1.10, p = 3.98 × 10<sup>-9</sup> ) in colorectal cancer, rs7086803 in lung cancer (OR = 1.30, p = 3.54 × 10<sup>-18</sup> ) and rs11196067 (OR = 1.18, p = 3.59 × 10<sup>-13</sup> ) in glioma, moderate for rs12255372 (OR = 1.12, p = 2.52 × 10<sup>-4</sup> ) in breast cancer and weak for rs7903146 (OR = 1.11, p = 0.007) in colorectal cancer. | 28949031 | 2018 |
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0.820 | GeneticVariation | BEFREE | The results indicated that the TCF7L2 rs11196172 polymorphism increases the risk of CRC independently, with no evidence of an interaction with diabetes or obesity. | 27792933 | 2016 |
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A | 0.820 | GeneticVariation | GWASCAT | Identification of Susceptibility Loci and Genes for Colorectal Cancer Risk. | 26965516 | 2016 |
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A | 0.820 | GeneticVariation | GWASCAT | Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk. | 24836286 | 2014 |
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A | 0.820 | GeneticVariation | GWASDB | Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk. | 24836286 | 2014 |