Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1805192
rs1805192
0.100 GeneticVariation BEFREE This meta-analysis suggests that the Ala allele of the PPARgamma P12A polymorphism might be a protective factor for colorectal cancer, but a risk factor for gastric cancer. 20596649

2010

dbSNP: rs1805192
rs1805192
0.100 GeneticVariation BEFREE PPAR-gamma 34 C>G is associated with colon cancer risk, but not associated with CRC and rectal cancer risk. 20440859

2010

dbSNP: rs1805192
rs1805192
0.100 GeneticVariation BEFREE A common polymorphism at codon 12 of this gene (Pro12Ala) has been shown to confer protection against diabetes and colorectal cancer. 17763950

2008

dbSNP: rs1805192
rs1805192
0.100 GeneticVariation BEFREE In this study, we evaluated the association between colorectal cancer and specific tumor mutations and the Pro12Ala (P12A) PPARgamma polymorphism. 16489531

2006

dbSNP: rs1805192
rs1805192
0.100 GeneticVariation BEFREE We studied the association of SNPs in the IL-6 (-174G>C), IL-8 (-251T>A), TNFalpha (-308G>A), ICAM-1 (R241G and K469E), and PPARgamma (Pro12Ala) genes and the risk of CRC. 16937502

2006

dbSNP: rs1805192
rs1805192
0.100 GeneticVariation BEFREE With adjustment for CRC risk factors, subjects with one or two copies of the G allele of the PPARgamma2 Pro12Ala polymorphism showed a statistically significant reduction in risk compared to those with the CC genotype [odds ratio (OR)=0.53, 95% confidence interval (CI)=0.30-0.92]. 16513680

2006

dbSNP: rs1805192
rs1805192
0.100 GeneticVariation BEFREE A common polymorphism at codon 12 of this gene (Pro12Ala) has been shown to confer protection against diabetes and colorectal cancer. 16393309

2006

dbSNP: rs1805192
rs1805192
0.100 GeneticVariation BEFREE Meat, milk, saturated fatty acids, the Pro12Ala and C161T polymorphisms of the PPARgamma gene and colorectal cancer risk in Japanese. 16965392

2006

dbSNP: rs1805192
rs1805192
0.100 GeneticVariation BEFREE After adjustment for age, sex, smoking habit, family history and family income, an increased risk of CRC was observed for the C/T + T/T genotype compared to the C/C genotype of the C161T polymorphism (odds ratio = 1.61, 95% confidence interval: 1.10-2.36), whereas no significant association was found for Pro12Ala (odds ratio = 1.06, 95% confidence interval: 0.70-1.61). 16108832

2005

dbSNP: rs1805192
rs1805192
0.100 GeneticVariation BEFREE We have studied the association between single nucleotide polymorphisms in the interleukin (IL)-6 (-174 G>C), IL8 (-251T>A), tumor necrosis factor alpha (-308G>A), and PPARG (Pro12Ala) genes and the risk of CRC in a group of 377 cases and 326 controls from Barcelona, Spain. 12839942

2003