Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs121913400
rs121913400
0.800 GeneticVariation UNIPROT Updated guidelines for biomarker testing in colorectal carcinoma: a national consensus of the Spanish Society of Pathology and the Spanish Society of Medical Oncology. 25373533

2015

dbSNP: rs121913400
rs121913400
0.800 GeneticVariation UNIPROT Tumor markers in colorectal cancer, gastric cancer and gastrointestinal stromal cancers: European group on tumor markers 2014 guidelines update. 23852704

2014

dbSNP: rs121913400
rs121913400
0.800 GeneticVariation UNIPROT Multitarget stool DNA testing for colorectal-cancer screening. 25006736

2014

dbSNP: rs121913400
rs121913400
0.800 GeneticVariation UNIPROT RAS testing of colorectal carcinoma—a guidance document from the Association of Clinical Pathologists Molecular Pathology and Diagnostics Group. 24996433

2014

dbSNP: rs121913400
rs121913400
0.800 GeneticVariation UNIPROT Recommendations from the EGAPP Working Group: can testing of tumor tissue for mutations in EGFR pathway downstream effector genes in patients with metastatic colorectal cancer improve health outcomes by guiding decisions regarding anti-EGFR therapy? 23429431

2013

dbSNP: rs121913400
rs121913400
0.800 GeneticVariation UNIPROT ESMO Consensus Guidelines for management of patients with colon and rectal cancer. a personalized approach to clinical decision making. 23012255

2012

dbSNP: rs121913400
rs121913400
0.800 GeneticVariation UNIPROT Guidelines for biomarker testing in colorectal carcinoma (CRC): a national consensus of the Spanish Society of Pathology (SEAP) and the Spanish Society of Medical Oncology (SEOM). 22855150

2012

dbSNP: rs121913400
rs121913400
0.800 GeneticVariation UNIPROT NCCN Task Force report: Evaluating the clinical utility of tumor markers in oncology. 22138009

2011

dbSNP: rs121913400
rs121913400
0.800 GeneticVariation UNIPROT National Academy of Clinical Biochemistry laboratory medicine practice guidelines for use of tumor markers in testicular, prostate, colorectal, breast, and ovarian cancers. 19042984

2008

dbSNP: rs121913400
rs121913400
0.800 GeneticVariation UNIPROT ASCO 2006 update of recommendations for the use of tumor markers in gastrointestinal cancer. 17060676

2006

dbSNP: rs121913400
rs121913400
A 0.800 CausalMutation CLINVAR

dbSNP: rs587776850
rs587776850
C 0.700 CausalMutation CLINVAR

dbSNP: rs775104326
rs775104326
T 0.700 CausalMutation CLINVAR

dbSNP: rs370662884
rs370662884
0.020 GeneticVariation BEFREE In conclusion, CCND1 870G/A and CDH1 -160C/A SNPs may modify the risk of CRC susceptibility in South Indian population. 25146682

2014

dbSNP: rs370662884
rs370662884
0.020 GeneticVariation BEFREE However, the CCND1 G870A polymorphism may modify the protective effect of postmenopausal hormone use on the development of CRC. 18196581

2008

dbSNP: rs13072632
rs13072632
0.010 GeneticVariation BEFREE We studied thirteen single nucleotide polymorphisms (SNPs) located in SFRP3 (rs7775), CTNNB1 (β-catenin) [rs4135385, rs13072632], APC (rs454886, rs459552), LRP6 (rs2075241, rs2284396), DKK4 (rs3763511), DKK3 (rs6485350), TCF4 (rs12255372) and AXIN2 (rs3923086, rs3923087, rs4791171) in patients with colorectal cancer (n = 122) and controls (n = 110). 31485167

2019

dbSNP: rs4135385
rs4135385
0.010 GeneticVariation BEFREE We studied thirteen single nucleotide polymorphisms (SNPs) located in SFRP3 (rs7775), CTNNB1 (β-catenin) [rs4135385, rs13072632], APC (rs454886, rs459552), LRP6 (rs2075241, rs2284396), DKK4 (rs3763511), DKK3 (rs6485350), TCF4 (rs12255372) and AXIN2 (rs3923086, rs3923087, rs4791171) in patients with colorectal cancer (n = 122) and controls (n = 110). 31485167

2019

dbSNP: rs1233296947
rs1233296947
0.010 GeneticVariation BEFREE The CRC colorectal cancer (CRC) cell lines HCT116 wild-type (wt), HCT116 p53-/-, and HT-29 (mutant; R273H) were employed, covering three different p53 variations. 28618116

2017

dbSNP: rs139085081
rs139085081
0.010 GeneticVariation BEFREE Here, we investigated, for the first time, the role of Arg324Gly (970C>G) along with Arg200Trp (598C>T) on colorectal cancer (CRC) risk by analyzing 659 patients and 607 control individuals drawn from the German DACHS (Darmkrebs: Chancen der Verhütung durch Screening) study. 17420170

2007