Gene: MSH6 ×
Source: BEFREE ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2020912
rs2020912
MSH6 ; FBXO11
0.710 GeneticVariation BEFREE No patients displayed a truncating mutation, and 1 CRC patient harbored a novel missense mutation (V878A). 12537658

2002
dbSNP: rs1042821
rs1042821
MSH6
0.030 GeneticVariation BEFREE In conclusion, our data suggests thatMSH6 Glu39Gly polymorphism is associated with the risk of developing sporadic colorectal cancer in polish population. 28451866

2018
dbSNP: rs1042821
rs1042821
MSH6
0.030 GeneticVariation BEFREE These findings suggest that hMSH6 Glu39Gly polymorphism is associated with the risk of developing colorectal cancer in the Polish population, probably due to a defective mismatch repair system. 29442465

2017
dbSNP: rs1042821
rs1042821
MSH6
0.030 GeneticVariation BEFREE The MSH6 G39E germline polymorphism is not associated with an increased risk of either microsatellite stable or unstable sporadic colorectal cancer. 19582761

2009
dbSNP: rs536562413
rs536562413
MSH6 ; FBXO11
0.010 GeneticVariation BEFREE Four single nucleotide polymorphisms in 3 mismatch repair genes (MSH3 R940Q, MSH3 T1036A, MSH6 G39E and MLH1 I219V) were genotyped in 237 colorectal cancer cases and a subcohort of 2,189 participants. 17205513

2007
dbSNP: rs984907158
rs984907158
MSH6 ; FBXO11
0.010 GeneticVariation BEFREE MSH2 118T>C and MSH6 159C>T promoter polymorphisms and the risk of colorectal cancer. 17942459

2007
dbSNP: rs63750258
rs63750258
MSH6 ; FBXO11
0.010 GeneticVariation BEFREE The Glu995STOP founder mutation is not a familial breast cancer predisposition allele and makes only a limited contribution to colorectal cancer burden in Finland. 15805151

2005