|
rs10159239
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The Single Nucleotide Polymorphism rs10159239 was examined by logistic regression with known risk factors for Coronary artery disease and remained significant (0.035).
|
31639433 |
2020 |
|
rs6721961
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, NRF2 rs6721961 associated with CAD and severity of coronary atherosclerosis.
|
31332605 |
2020 |
|
rs72658855
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A non-significant association was reported in recessive inheritance model for variant (CC+CT) vs. TT OR 0.56(0.16-1.95), P<0.36. and in dominant inheritance model for variant CC vs. (CT+TT) OR 2.8(1.07-7.34),P<0.032 .In case of allelic comparison, it was indicated that the LDLR rs2228671-T allele was associated with an increased risk of developing risk of CAD compared to C allele OR=2.4, 95% CI (1.05-5.64) P< 0.036 .Our findings showed that LDLR rs72658855 C>T gene variability is associated with an increased susceptibility to coronary artery disease in codominant inheritance model for variant CC vs. CT OR 1.7(1.1-2.6), P<0.015 and in dominant inheritance model for variant CC vs. (CT+TT) OR 1.66(1.07-2.58),P<0.0.02.
|
31613733 |
2020 |
|
rs756601757
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We speculate that this mutation [Arg196Trp] in the USF1 gene might be associated with FCHL and early-onset coronary heart disease in this family.
|
31725952 |
2020 |
|
rs972655070
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We speculate that this mutation [Arg196Trp] in the USF1 gene might be associated with FCHL and early-onset coronary heart disease in this family.
|
31725952 |
2020 |
|
rs10455872
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Using the ICD-9-CM and ICD-10-CM maps, we conducted a PheWAS with a Lipoprotein(a) genetic variant, rs10455872, which replicated two known genotype-phenotype associations with similar effect sizes: coronary atherosclerosis (ICD-9-CM: P<.001; odds ratio (OR) 1.60 [95% CI 1.43-1.80] vs ICD-10-CM: P<.001; OR 1.60 [95% CI 1.43-1.80]) and chronic ischemic heart disease (ICD-9-CM: P<.001; OR 1.56 [95% CI 1.35-1.79] vs ICD-10-CM: P<.001; OR 1.47 [95% CI 1.22-1.77]).
|
31553307 |
2019 |
|
rs1051339
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Further, we characterized a second common exonic coding variant (rs1051339), which is predicted to alter LIPA signal peptide cleavage similarly to rs1051338, yet is not linked to intronic variants. rs1051339 also does not impact LIPA function in vitro and confers no coronary artery disease risk.
|
31645127 |
2019 |
|
rs11057830
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three single nucleotide polymorphisms (SNPs) identified in a genome-wide analysis study including 7781 individuals of European descent, rs964184, rs2108622, and rs11057830 were used as the genetic instruments for vitamin E. Data for CAD/myocardial infarction (MI) were available from Coronary ARtery DIsease Genome wide Replication and Meta-analysis (CARDIoGRAM) plus The Coronary Artery Disease (C4D) Genetics consortium.
|
31505768 |
2019 |
|
rs11614913
|
|
|
0.010 |
GeneticVariation |
BEFREE |
miR-196a2 (rs11614913) polymorphism is associated with coronary artery disease, but not with in-stent coronary restenosis.
|
30560371 |
2019 |
|
rs11646692
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In dyslipidemia patients, rs12934922 and rs11646692 may influence the development of coronary atherosclerosis.
|
30896431 |
2019 |
|
rs12704673
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two novel loci were associated with birthweight and adult coronary artery disease (rs2870463 in CTRB1) and with birthweight and adult waist circumference (rs12704673 in CALCR).
|
30858448 |
2019 |
|
rs12934922
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In dyslipidemia patients, rs12934922 and rs11646692 may influence the development of coronary atherosclerosis.
|
30896431 |
2019 |
|
rs139401390
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genome-wide association study suggests impact of chromosome 10 rs139401390 on kidney function in patients with coronary artery disease.
|
30809046 |
2019 |
|
rs146292819
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association of rs146292819 Polymorphism in ABCA1 Gene with the Risk of Coronary Artery Disease in Pakistani Population.
|
30945099 |
2019 |
|
rs17366743
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The goal of the study was to assess associations of rs17300539, rs266729, rs182052, rs2241766, and rs17366743 single nucleotide polymorphisms (SNPs) of the <i>ADIPOQ</i> gene with concentrations of serum adiponectin and with coronary atherosclerosis and type 2 diabetes mellitus in 447 patients (316 men and 131 women) subjected to coronary angiography.
|
31561637 |
2019 |
|
rs174547
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the secondary analysis, the minor allele of rs174547 in <i>FADS1</i> was associated with significantly lower odds of any ischemic stroke, large-artery stroke, and venous thromboembolism and showed suggestive evidence of inverse association with coronary artery disease, abdominal aortic aneurysm and aortic valve stenosis.
|
31817859 |
2019 |
|
rs1761667
|
|
|
0.010 |
GeneticVariation |
BEFREE |
CD36 gene polymorphism rs1761667 (G > A) is associated with hypertension and coronary artery disease in an Iranian population.
|
31185924 |
2019 |
|
rs1799750
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association of MMP-1 (rs1799750)-1607 2G/2G and MMP-3 (rs3025058)-1612 6A/6A Genotypes With Coronary Artery Disease Risk Among Iranian Turks.
|
31356534 |
2019 |
|
rs1800795
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Additionally, we found that carriers of the <i>C</i> allele of 174<i>G>C</i> (rs1800795) polymorphism have an increase in the risk of coronary artery disease under the hereditary models assessed in the study.
|
31338006 |
2019 |
|
rs1800872
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association of IL-8-251 A/T rs4073 and IL-10 rs1800872 -592C/A Polymorphisms and Coronary Artery Disease in North Indian Population.
|
30073578 |
2019 |
|
rs182052
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Regression analysis revealed an increase in prevalence of unstable angina (OR (odds ratio) = 2.55; 95%CI 1.4-4.82; p = 0.018) and coronary artery disease (OR = 1.55; 95%CI 1.15-2.09; p = 0.021) per copy of the rs182052 A allele.
|
31561637 |
2019 |
|
rs184003
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs184003 SNP seems related to coronary artery disease, breast cancer, and diabetes.
|
30863465 |
2019 |
|
rs2292832
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Previous studies have linked miRNA-149 to cancers, and rs2292832 T>C is related to allergic diseases and inflammatory bowel disease, which both show immune system disorders and coronary artery disease.
|
31785027 |
2019 |
|
rs2855262
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Gene polymorphisms: <i>SOD2</i> rs4880, <i>SOD3</i> rs2536512 and rs2855262, <i>GPX</i> rs3828599, and <i>GSTT1</i> (deletion) were evaluated the associations with HTG, low HDL-C, high TG/HDL-C ratio, and severity of coronary atherosclerosis.
|
31396447 |
2019 |
|
rs2870463
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two novel loci were associated with birthweight and adult coronary artery disease (rs2870463 in CTRB1) and with birthweight and adult waist circumference (rs12704673 in CALCR).
|
30858448 |
2019 |