Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs505151
rs505151
0.040 GeneticVariation BEFREE The associations between proprotein convertase subtilisin/kexin type 9 E670G polymorphism and the risk of coronary artery disease and serum lipid levels: a meta-analysis. 26576960

2015

dbSNP: rs505151
rs505151
0.040 GeneticVariation BEFREE Effect of E670G Polymorphism in PCSK9 Gene on the Risk and Severity of Coronary Heart Disease and Ischemic Stroke in a Tunisian Cohort. 24599757

2014

dbSNP: rs505151
rs505151
0.040 GeneticVariation BEFREE The PCSK9 gene E670G polymorphism affects low-density lipoprotein cholesterol levels but is not a risk factor for coronary artery disease in ethnic Chinese in Taiwan. 19191720

2009

dbSNP: rs505151
rs505151
0.040 GeneticVariation BEFREE Haplotype 3 encompassing the E670G variant is an independent determinant of plasma LDL-C levels and the severity of coronary atherosclerosis. 15893176

2005

dbSNP: rs11591147
rs11591147
0.020 GeneticVariation BEFREE The single-nucleotide polymorphism (SNP) rs11591147 has been associated with lower LDL-cholesterol and a lower risk of coronary heart disease. 23300213

2013

dbSNP: rs11591147
rs11591147
0.020 GeneticVariation BEFREE This is probably due to the combined effect of the low frequency of R46L among Italians and of the young age of the analyzed cohort for whom the impact of coronary atherosclerosis is less important. 20699424

2010