| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
0.060 | GeneticVariation | BEFREE | Association between Toll-like receptor 4 Asp299Gly polymorphism and coronary heart disease susceptibility. | 28793055 | 2017 |
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|
0.060 | GeneticVariation | BEFREE | TLR4 gene polymorphism (Asp299Gly) attenuates innate immune responsiveness, reduces the risk for coronary artery disease, and increases a chance of longevity. | 19273219 | 2009 |
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|
0.060 | GeneticVariation | BEFREE | We studied the TLR4 gene Asp299Gly polymorphism in relation to susceptibility to myocardial infarction in a cohort of patients with angiographically documented coronary artery disease, and performed a meta-analysis using data sets from three independent studies. | 15864121 | 2005 |
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|
0.060 | GeneticVariation | BEFREE | Toll-like receptor 4 gene Asp299Gly polymorphism is associated with reductions in vascular inflammation, angiographic coronary artery disease, and clinical diabetes. | 15632890 | 2004 |
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|
0.060 | GeneticVariation | BEFREE | Among symptomatic men with documented coronary artery disease, the TLR4 Asp299Gly polymorphism was associated with the risk of cardiovascular events. | 12742999 | 2003 |
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|
0.060 | GeneticVariation | BEFREE | The findings of this study do not support the hypothesis that the TLR4 Asp299Gly polymorphism influences predisposition to and progression of coronary artery disease. | 12957699 | 2003 |
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|
0.010 | GeneticVariation | BEFREE | Toll-like receptor 4 rs11536889 is associated with angiographic extent and severity of coronary artery disease in a Chinese population. | 28002812 | 2017 |
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|
0.010 | GeneticVariation | BEFREE | Two polymorphisms of the TLR4 gene (Asp299Gly and Thr399Ile) were determined in 655 men with angiographically documented coronary atherosclerosis. | 12742999 | 2003 |